Patrick Vallance
HonFREng | |
---|---|
Born | Patrick John Thompson Vallance 17 March 1960[2] Essex, United Kingdom |
Education | Truro School |
Alma mater | St George's, University of London (BSc, MBBS) |
Spouse |
Sophia Ann Dexter (m. 1986)GlaxoSmithKline |
Website | www |
Sir Patrick John Thompson Vallance
From 1986 to 1995, Vallance taught at
Early life and education
Patrick Vallance was born on 17 March 1960 to Peter and Barbara Vallance, in south-west
In 1978, Vallance gained admission to study medicine at St George's, University of London, where he was taught by Joe Collier, Professor of Medicines Policy,[1][5][6] and from where he received a Bachelor of Science degree in 1981 followed by a Bachelor of Medicine, Bachelor of Surgery (MBBS) in 1984.[2] In addition to Collier, he has been inspired by physician Tom Pilkington and former Regius Professor of Physic at Cambridge, Sir Keith Peters.[5]
Career and research
Prior to taking up senior positions with the pharmaceutical company
St George's Hospital
From 1986 to 1995 he taught at St George's Hospital Medical School,
In 1987, with
University College Hospital
From 1995 to 2002 he was a professor at
GlaxoSmithKline
In 2006, in his mid-40s, he joined GSK as head of drug discovery.[20][21] Four years later he became head of medicines discovery and development, and in 2012 he was appointed head of research and development at GSK.[22][23][24][25][26] Under his leadership, new medicines for cancer, asthma, autoimmune diseases and HIV infection were discovered and approved for use worldwide. He championed open innovation and novel industry-academic partnerships globally,[9][27][25] and maintained a focus on the search for new antibiotics and treatments for tropical diseases.[9][28]
UK Government
In March 2018, Vallance left GSK, and on 4 April 2018 he began his five-year tenure as Chief Scientific Adviser to the UK Government, replacing the interim officeholder Chris Whitty.[29] In this role he led the Government Office for Science, advising the prime minister and the cabinet.[30][31] In 2018, he was one of nine scientific advisers who, in a paper in Nature, called for "inclusive, rigorous, transparent, and accessible information for policy makers" and supported the Evidence-Based Research Network, established in 2016, to "lobby for all proposals for new research to be supported by references to systematic reviews of relevant existing research".[32]
COVID-19 pandemic
In March 2020, as the government's Chief Scientific Adviser, Vallance appeared alongside prime minister
In September, it emerged that Vallance owns a deferred bonus of 43,111 shares worth £600,000 in GlaxoSmithKline, a company which is working on developing a COVID vaccine.[36] This led to claims of a potential conflict of interest, as Vallance could be seen to have a financial interest in pushing for a vaccine-based response to the pandemic whether or not this is objectively the best approach.[37] Then Health Secretary Matt Hancock denied that this was the case, with a government spokesperson stating that, "Upon his appointment, appropriate steps were taken to manage the Government Chief Scientific Adviser's interests in line with advice provided at the time. The GCSA has no input into contractual and commercial decisions on vaccine procurement which are taken by Ministers following a robust cross-Government approvals regime".[38]
After a televised briefing alongside Johnson and Whitty on 31 October, where a second "lockdown" was introduced for England, Vallance was criticised for showing two slides – projecting hospital admissions and deaths – which were later reissued with worst-case figures revised downward.
Selected publications
His publications[8] include:
- Hyperdynamic circulation in cirrhosis: a role for nitric oxide?[44]
- Physiological importance of nitric oxide[45]
- Exploring vascular nitric oxide in health and disease[1]
- Nitric oxide in the human cardiovascular system[46]
- Sildenafil: desired and undesired effects[47]
- Four principles to make evidence synthesis more useful for policy[48]
Honours and awards
In 1995, Vallance was elected a
Vallance was
Personal life
Vallance married Sophia Ann Dexter in 1986; they have two sons and one daughter.[2] Dexter is a former general practitioner (GP) and honorary tutor at St. George's Hospital Medical School.[55]
References
- ^ PMID 9192338.
- ^ a b c d e f g h i
Anon (2017). "Vallance, Sir Patrick (John Thompson)". doi:10.1093/ww/9780199540884.013.U246054. (Subscription or UK public library membershiprequired.)
- ^ "Natural History Museum appoints Patrick Vallance as chair". February 2022.
- ^ Can Data Make a Medicine?, YouTube video, Royal Institution (2017)
- ^ S2CID 5081180.(subscription required)
- ^ a b "Career profile; Patrick Vallance". St George's Alumni Newsletter; The magazine for Alumni and friends of St George’s, University of London. Issue 16 (spring 2013), p.18-19.
- from the original on 12 January 2022. Retrieved 18 March 2020.
- ^ a b Patrick Vallance publications indexed by the Scopus bibliographic database. (subscription required)
- ^ a b c d e f g Anon (2017). "Patrick Vallance". royalsociety.org. London: Royal Society. Retrieved 19 March 2020.
- SAGE Journals.
- PMID 10637204.
- PMID 10336566.
- ISBN 978-94-007-1042-9.
- PMID 10972702.
- S2CID 9790385.
- ISBN 978-0-309-45565-7.)
{{cite book}}
: CS1 maint: multiple names: authors list (link - PMID 15994605.
- PMID 15863758.
- PMID 16055914.
- PMID 17463447.
- ^ "Dr Patrick Vallance: President, R&D". gsk.com. Archived from the original on 29 July 2017.
- ^ Jim Al-Khalili (2015). "The Life Scientific interviews Patrick Vallance on pharmaceuticals". bbc.co.uk. BBC.
- ^ Cohen, Deborah (2012). "The End of Drug Discovery". bbc.co.uk. BBC.
- S2CID 11104458.
- ^ ISSN 1744-7933.
- ISBN 978-0-7456-8915-9.
- S2CID 4395455.
- ^ Evanson, Deborah; Narcross, Jon (4 May 2016). "Imperial celebrates over 3,000 graduating students | Imperial News | Imperial College London". Imperial News. Retrieved 21 March 2020.
- PMID 29144475. Retrieved 21 March 2020.
- ^ "Appointment of Dr Patrick Vallance as government Chief Scientific Adviser". Cabinet Office. 8 November 2017. Retrieved 9 November 2017.
- ^ "Patrick Vallance, President, R&D, GSK to become UK Government's Chief Scientific Adviser". GlaxoSmithKline. 8 November 2017. Retrieved 7 September 2018.
- S2CID 53294156.
- PMID 32071448.
- ^ "Government is listening to scientists on coronavirus response, Vallance says | Civil Service World". civilserviceworld.com. Retrieved 24 March 2020.
- ^ Heather Stewart; Mattha Busby (13 March 2020). "Coronavirus: science chief defends UK plan from criticism". The Guardian. Retrieved 5 July 2020.
- ^ Roach, April (24 September 2020). "Matt Hancock denies conflict of interest in Patrick Vallance holding vaccine company shares". Evening Standard. Retrieved 26 September 2020.
- ^ Hymas, Charles (23 September 2020). "Revealed: Sir Patrick Vallance has £600,000 shareholding in firm contracted to develop vaccines". The Daily Telegraph. Archived from the original on 12 January 2022. Retrieved 26 September 2020.
- ^ Jimenez, Darcy (24 September 2020). "UK's chief scientific adviser Patrick Vallance has £600,000 of shares in vaccine maker GSK". Metro. Retrieved 26 September 2020.
- ^ Press Association (6 November 2020). "Government criticised after errors emerge in key Covid-19 projections". Glasgow Times. Retrieved 7 November 2020.
- ^ Conway, Ed (6 November 2020). "Coronavirus: Disturbing lack of transparency risks undermining lockdown". Sky News. Retrieved 7 November 2020.
- ^ "Slides and datasets to accompany coronavirus press conference: 31 October 2020". GOV.UK. Prime Minister's Office. 3 November 2020. Retrieved 7 November 2020.
- ^ "Covid: Regulator criticises data used to justify lockdown". BBC News. 5 November 2020. Retrieved 7 November 2020.
- ^ "OSR Statement regarding transparency of data related to COVID-19". Office for Statistics Regulation. 5 November 2020. Retrieved 7 November 2020.
- S2CID 35521040.
- PMID 2059682.
- PMID 9643614.
- PMID 10476234.
- PMID 29925978.
- PMID 15566617.
- ^ "Royal Academy of Engineering welcomes 72 new Fellows". Royal Academy of Engineering. Retrieved 26 September 2022.
- ^ "Patrick Vallance knighted in 2019 New Year's Honours". British Pharmacological Society. 29 December 2018. Retrieved 7 February 2019.
- ^ "No. 63571". The London Gazette (Supplement). 1 January 2022. p. N3.
- ^ "New Year Honours: Whitty, Van-Tam and Blair knighted, Lumley and Redgrave made dames". BBC News. 31 December 2021. Retrieved 31 December 2021.
- ^ Royal Medal 2023
- ^ "Our Trustees". Cardboard Citizens. Retrieved 24 September 2020.