James Aguayo-Martel

otolaryngology (ENT), and plastic surgery, Sutter Roseville Medical Center. He is the former director of ophthalmology, Sutter General and Memorial Hospitals and assistant professor of ophthalmology and radiology, Johns Hopkins Medical School and Wilmer Ophthalmological Institute. He is currently clinical professor of ophthalmology and associate dean of graduate medical education in California Northstate University College of Medicine

NMR spectroscopy to study tissue metabolism non-destructively.^[2] The research was able to demonstrate the conversion of glucose to sorbitol in the single intact lens which supported the hypothesis that sorbitol led tissue damage in diabetes. The condition of diabetes leads to uncontrolled levels of glucose in the body. The ability to monitor glucose and its metabolism in by non-invasive methodology in living tissue allows facilitated the understanding of this disease state.^{[citation needed}

non-linear regression analysis.^{[citation needed}

vitreous using NMR spectroscopy and imaging.^[6][7]

hexose monophosphate shunt, glycolysis, and the polyol pathway) in the single living lens which allowed insight into the study of diabetic cataractogenesis.^[12] and applied to corneal tissue transplantation.^[13] His work culminated in the development of chemical shift NMR Microscopy, which combined Magnetic Resonance imaging (MRI) and spectroscopy analysis while working at the Francis Bitter National Magnet Laboratory, Massachusetts Institute of Technology. His research team applied the technique to the study of the living lens to study diabetic cataractogenesis.^[14]

medications (aldose reductase inhibitor) to prevent eye and nerve damage in people with diabetes. He has been noted for his work in low illumination ophthalmoscopy and co-inventing the technique of Intraepikeratophakia^[15][16][17] a precursor to the technique of LASIK

Fellow of the American College of Surgeons and the American Academy of Ophthalmology.^{[citation needed}