Martin Barratt
Martin Barratt | |
---|---|
Hemolytic-uremic syndrome.[1] | |
Scientific career | |
Fields | paediatric nephrology |
Institutions | St Thomas' Hospital, Johns Hopkins School of Medicine, Great Ormond Street Hospital |
Thomas Martin Barratt
Life
Barratt's father owned and ran a law firm, and his mother was one of the first women to matriculate at
Throughout his life, Barratt suffered from facioscapulohumeral muscular dystrophy, a disease that causes progressive weakness, which forced him to retire early, eventually forcing him to use wheelchair for movement. In retirement he kept up to date with the latest developments in paediatric nephrology.[1]
Career
Barratt completed his clinical training at
In 1966 Barratt married Gill Owen, a
Contributions
Research
When Barratt started his clinical career, the specialism of paediatric nephrology in the UK, outwith certain areas, was primitive.[1] Barratt held the first post that was specifically committed, both academically and professionally to the treatment of children with renal disease.[1]
Barratt initially worked by himself, but was joined by Michael Dillon in 1975, and together they built a major world class paediatric nephrology services department at Great Ormond Street Hospital and conducted a research programme at the Institute of Child Health. Barratt was later joined by Richard Trompeter and Lesley Rees who continued the work of Barratt.[1]
Barratt early in his career realized that collaboration was needed in developing an interdisciplinary care model for the treatment of children with renal diseases, eventually working closely with the paediatric urologists David Innes Williams and Philip G. Ransley and the paediatric imager, Isky Gordon.[1]
Barratt had a broad research focus, conducting research into
- Clinically, Martin had the most wonderful clarity of thought—making the most complex issues clear. He had an absolute belief that the job of a consultant was to offer patients the best of all available evidence.[3]
Barratt was considered an outstanding teacher and lecturer.[1]
Association work
From 1972 to 1976, Barratt was secretary of the British Association for Paediatric Nephrology, and from 1994 to 1997 he was president of the association.[1] Barratt worked with the European Society for Paediatric Nephrology and the International Pediatric Nephrology Association. After his retirement, in 1998, Barratt was co-president along with the paediatrician Sir Cyril Chantler of the 11th Congress of the International Pediatric Nephrology Association.
Bibliography
The following papers were his most well known and cited:
- Smellie, Jean M.; Barratt, T. Martin; Chantler, Cyril; Gordon, Isky; Prescod, Nina P.; Ransley, Philip G.; Woolf, Adrian S. (2001). "Medical versus surgical treatment in children with severe bilateral vesicoureteric reflux and bilateral nephropathy: a randomised trial". The Lancet. 357 (9265): 1329–1333. PMID 11343739.
- Levinsky, Roland J.; Barratt, T. Martin (1979). "IgA IMMUNE COMPLEXES IN HENOCH-SCHÖNLEIN PURPURA". The Lancet. 314 (8152): 1100–1103. PMID 91839.
- Walters, Martin D. S.; Matthei, I. Ute; Kay, Richard; Dillon, Michael J.; Barratt, T. Martin (June 1989). "The polymorphonuclear leucocyte count in childhood haemolytic uraemic syndrome". Pediatric Nephrology. 3 (2): 130–134. .
- Rossetti, S.; Burton, Sarah; Strmecki, Lana; Pond, Gregory R.; San Millán, Jośe L.; Zerres, Klaus; Barratt, T. Martin; Ozen, Seza; Torres, Vicente E.; Bergstralh, Erik J.; Winearls, Christopher G.; Harris, Peter C. (1 May 2002). "The Position of the Polycystic Kidney Disease 1 (PKD1) Gene Mutation Correlates with the Severity of Renal Disease". Journal of the American Society of Nephrology. 13 (5): 1230–1237. . Retrieved 31 July 2018.
- Roy, Sushmita; Dillon, Michael J.; Trompeter, Richard S.; Barratt, T. Martin (26 May 1997). "Autosomal recessive polycystic kidney disease: long-term outcome of neonatal survivors". Pediatric Nephrology. 11 (3): 302–306. .
- Rossetti, Sandro; Kubly, Vickie J.; Consugar, Mark B.; Hopp, Katharina; Roy, Sushmita; Horsley, Sharon W.; Chauveau, Dominique; Rees, Lesley; Barratt, T. Martin; van't Hoff, William G.; Niaudet, W. Patrick; Torres, Vicente E.; Harris, Peter C. (April 2009). "Incompletely penetrant PKD1 alleles suggest a role for gene dosage in cyst initiation in polycystic kidney disease". Kidney International. 75 (8): 848–855. PMID 19165178.
- Fizpatrick, Margaret M.; Walters, Martin D.S.; Trompeter, Richard S.; Dillon, Michael J.; Barratt, T. Martin (April 1993). "Atypical (non-diarrhea-associated) hemolytic-uremic syndrome in childhood". The Journal of Pediatrics. 122 (4): 532–537. PMID 8463896.
- Forsyth, KevinD; Fitzpatrick, MargaretM; Simpson, AnnaC; Barratt, T.Martin; Levinsky, RolandJ (August 1989). "NEUTROPHIL-MEDIATED ENDOTHELIAL INJURY IN HAEMOLYTIC URAEMIC SYNDROME". The Lancet. 334 (8660): 411–414. PMID 2569599.
- Fitzpatrick, Margaret M.; Shah, Vanita; Trompeter, Richard S.; Dillon, Michael J.; Barratt, T. Martin (October 1992). "Interleukin-8 and polymorphoneutrophil leucocyte activation in hemolytic uremic syndrome of childhood". Kidney International. 42 (4): 951–956. .
- Fitzpatrick, M M; Shah, V; Trompeter, R S; Dillon, M J; Barratt, T M (31 August 1991). "Long term renal outcome of childhood haemolytic uraemic syndrome". BMJ. 303 (6801): 489–492. PMID 1912857.
- Brock, Penelope R.; Koliouskas, Dimitri E.; Barratt, T. Martin; Yeomans, Elizabeth; Pritchard, Jon (April 1991). "Partial reversibility of cisplatin nephrotoxicity in children". The Journal of Pediatrics. 118 (4): 531–534. .
- Levinsky, Roland J.; Malleson, Peter N.; Barratt, T. Martin; Soothill, John F. (19 January 1978). "Circulating Immune Complexes in Steroid-Responsive Nephrotic Syndrome". New England Journal of Medicine. 298 (3): 126–129. PMID 619241.
Barratt collaborated in the following books.
- Urology in Childhood., D Innes Williams; T Martin Barratt; Herbert B Eckstein; Sheila M Kohlinsky; George H Newns; Paul E Polani; Jack D Singer. Berlin, Heidelberg:Springer Berlin Heidelberg, 1974
- Pediatric nephrology., T Martin Barratt. Baltimore, Md. : Lippincott Williams & Wilkins, 1999
Awards and honours
In 1997 Barratt was appointed Commander of the Order of the British Empire (CBE) for services to children and awarded the prestigious James Spence Medal in 2002.[4]
References
- ^ PMID 24682468.
- ^ a b c d Levin, Michael (3 February 2014). "Martin Barratt obituary". Guardian News and Media Limited. The Guardian. Retrieved 29 July 2018.
- ^ .
- ^ a b c d e f "Professor Martin Barratt". The Royal College of Paediatrics and Child Health. The Royal College of Paediatrics and Child Health. 28 February 2017. Retrieved 29 July 2018.