Melanoma-associated antigen
MAGE family | |||||||||||
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Identifiers | |||||||||||
Symbol | MAGE | ||||||||||
SCOP2 | 1i4f / SCOPe / SUPFAM | ||||||||||
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The mammalian members of the MAGE (melanoma-associated antigen) gene family were originally described as completely silent in normal adult tissues, with the exception of male germ cells and, for some of them,
MAGE-like genes have also been identified in non-mammalian species, like the zebrafish or Drosophila melanogaster. Although no MAGE homologous sequences have been identified in Caenorhabditis elegans, Saccharomyces cerevisiae or Schizosaccharomyces pombe, MAGE sequences have been found in several plant species, including Arabidopsis thaliana.[1]
The only region of
Human proteins containing this domain
MAGE-B1; MAGEA1; MAGEA10; MAGEA11; MAGEA12; MAGEA2B; MAGEA3; MAGEA4; MAGEA6; MAGEA8; MAGEA9; MAGEB1; MAGEB10; MAGEB16; MAGEB18; MAGEB2; MAGEB3; MAGEB4; MAGEB5; MAGEB6; MAGEB6B; MAGEC1; MAGEC2; MAGEC3; MAGED1; MAGED2; MAGED4; MAGEE1; MAGEE2; MAGEF1; MAGEH1; MAGEL2; NDN; NDNL2;
References
- ^ PMID 11454705.