Mixed autoimmune hemolytic anemia
| Mixed autoimmune hemolytic anemia | |
|---|---|
| Specialty | Hematology |
Mixed autoimmune hemolytic anemia (MAIHA) is a type of
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People diagnosed with warm autoimmune hemolytic anemia (WAIHA) caused by
IgM) antibodies. These antibodies are active at room temperature, but are believed to be harmless since they are not the main antibodies responsible for WAIHA.[citation needed
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However, studies revealed the existence of a few cases of WAIHA that may also carry
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Mixed warm and cold AIHA runs a chronic course with severe intermittent exacerbations, such as serious anemia, and is treated by
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In the past, there were two obvious sources of error regarding the diagnosis of AIHA. First, patients with w-AIHA can produce low-titer, low-thermal amplitude CA of no clinical significance. Second, up to 20% of patients with CAD have IgG on the RBC surface in addition to C3d.[7][1][6][non-primary source needed]