Nigel Scrutton

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Nigel Scrutton
FRS FRSB FRSC
Image of Nigel Scrutton (MIB Director) taken in 2015
Born
Nigel Shaun Scrutton

(1964-04-02) 2 April 1964 (age 60)
Batley, West Riding of Yorkshire
NationalityBritish
CitizenshipBritish
Alma mater
Awards
Scientific career
Fields
Quantum Biology
Institutions
ThesisMechanistic and structural studies on glutathione reductase by protein engineering (1988)
Doctoral advisorRichard Perham
Websitewww.research.manchester.ac.uk/portal/Nigel.Scrutton.html

Nigel Shaun Scrutton (born 2 April 1964)

Biophysical Chemistry in the Department of Chemistry at the University of Manchester.[2] He is former Director of the Manchester Institute of Biotechnology (MIB) (2010 to 2020).[3]

Early life and education

Scrutton was born in

Churchill College, Cambridge (1992–95). He was awarded a Doctor of Science (ScD) degree in 2003 by the University of Cambridge
.

Career and research

Following his PhD, Scrutton was appointed as Lecturer (1995), then Reader (1997) and Professor (1999) at the

Royal Society University Research Fellow and Royal Society Wolfson Research Merit Award), the Lister Institute of Preventive Medicine, the Biotechnology and Biological Sciences Research Council (BBSRC) and the Engineering and Physical Sciences Research Council (EPSRC). He has been Visiting Professor at Tsinghua University (Beijing, China) and Cardiff University (UK), and adjunct professor at VISTEC (Thailand) and Beijing University of Chemical Technology
(China).

He has made major contributions to the study of

coenzyme specificity of an enzyme,[6] the establishment of automated microorganism bioengineering platforms for the production of chemicals (e.g. fuels, materials, active pharmaceutical ingredients) and the discovery of new riboflavin
cofactors.

His research has been funded by the

postdoctoral research
workers. He has published over 500 research papers and several patents.

In 2015 Scrutton co-founded the company C3 Biotechnologies Ltd to commercialise technologies for fuels and chemicals production, and subsidiary companies C3 Biotechnologies (Maritime and Aerospace, UK) Ltd in 2020, and C3 Biotechnologies (Maritime and Aerospace, USA) Inc in 2022.

He is Director of the Manchester Synthetic Biology Research Centre SYNBIOCHEM, which he established in 2014 following major investment by the UK government in

BBSRC
Council.

Under his leadership as Director, the enterprising vision of MIB was recognised by the award of the

Queen's Anniversary Prize
for Higher and Further Education (2018–20) as 'a leader in the UK’s strategic development of biotechnology and bio-manufacturing, through innovative technologies in partnerships with industry'.

Awards and honours

Scrutton was awarded the Colworth Medal in 1999[1] from the Biochemical Society; the Enzyme Chemistry Award (Charmian Medal) from the Royal Society of Chemistry in 2002; the Rita and John Cornforth Award from the Royal Society of Chemistry in 2009; the Interdisciplinary Prize from the Royal Society of Chemistry in 2019.

Scrutton was elected a

Lister Institute
in 2004.

He is recipient of a number of academic awards including: Sambrooke Exhibition Prize (King's College London, University of London, 1983); William Robson Prize (King's College London, University of London, 1985); Benefactors' Scholarship (St John's College, University of Cambridge, 1985); Henry Humphreys Research Prize / Research Fellowship (St John's College, University of Cambridge, 1989).

Personal life

Scrutton married Nia Francis Roberts in 1989 with whom he has two sons and one daughter.

References

  1. ^
    PMID 10830100
    .
  2. ^
    PMID 33373117
    .
  3. ^ a b "New director for Manchester Interdisciplinary Biocentre". University of Manchester. Retrieved 6 October 2016.
  4. OCLC 557267794
    .
  5. ^ "Nigel Scrutton". University of Manchester. Retrieved 6 October 2016.
  6. ^
    S2CID 1580419
    .
  7. S2CID 27201250
    .
  8. PMID 10074378
    .
  9. PMID 8870640
    .
  10. ^ Anon (2016). "UK Government Grants awarded to Nigel Scrutton". gtr.rcuk.ac.uk. Swindon: Research Councils UK. Archived from the original on 19 March 2016.
  11. ^ Adalbjörnsson, Björn Vidar (2012). Thermophilic old yellow enzyme : structure and kinetic characterisation (PhD thesis). University of Manchester. Open access icon
  12. ^ Guerriero, Andrew (2012). Variable pressure NMR analyses to assess compressive motion in PETNR and catalytically germane PETNR:Ligand complexes (PhD thesis). University of Manchester. Open access icon
  13. ^ Hare, Victoria (2012). PETN reductase as a versatile biocatalyst for the reduction of nitroalkenes (PhD thesis). University of Manchester. Open access icon
  14. ^ Hulley, Martyn (2010). Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates (PhD thesis). University of Manchester. Open access icon
  15. ^ Lou, Xiao (2010). Biochemical and structural studies of human methionine synthase reductase (PhD thesis). University of Manchester. Open access icon
  16. ^ Peers, Martyn (2013). Ruthenium(II) and iridium(III) complexes as photosensitisers towards light-driven biocatalysis (PhD thesis). University of Manchester. Open access icon
  17. ^ Russell, Henry (2013). Infrared and UV-visible time-resolved techniques for the study of tetrapyrrole-based proteins (PhD thesis). University of Manchester. Open access icon

External links

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