Nobiletin
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| Names | |
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| IUPAC name
3′,4′,5,6,7,8-Hexamethoxyflavone
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| Systematic IUPAC name
2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one | |
| Other names
Hexamethoxyflavone
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| Identifiers | |
3D model (
JSmol ) |
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| ChEBI | |
| ChemSpider | |
| KEGG | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C21H22O8 | |
| Molar mass | 402.399 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Nobiletin is a
bulbectomy-induced memory impairment.[1]
Potential pharmacology
Nobiletin was found to potentially inhibit cartilage degradation.[2]
Nobiletin was shown to augment
colon carcinogenesis have been described.[4]
Nobiletin enhances antitumor efficacy via suppression of IκB/NF-κB signaling in triple-negative breast cancer[5].
References
[5] Kim E, Kim YJ, Ji Z, Kang JM, Wirianto M, Paudel KR, Smith JA, Ono K, Kim JA, Eckel-Mahan K, Zhou X. ROR activation by Nobiletin enhances antitumor efficacy via suppression of IκB/NF-κB signaling in triple-negative breast cancer. Cell death & disease. 2022 Apr 19;13(4):374.
External links
- Nobiletin, phytochemicals.info