Tricetin
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IUPAC name
3′,4′,5,5′,7-Pentahydroxyflavone
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Systematic IUPAC name
5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one | |
Identifiers | |
3D model (
JSmol ) |
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ChemSpider | |
ECHA InfoCard
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100.237.320 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C15H10O7 | |
Molar mass | 302.23 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Tricetin is a
Leptospermoideae, such as Eucalyptus globulus.[1] This compound shows anticancer effects on human breast adenocarcinoma MCF-7 cells.[2] Moreover. a potent anti-inflammatory effect of tricetin has also been demonstrated in a model of acute pancreatitis.[3] This observation was explained by the compound's radical scavenging effects, its inhibitory effect on the DNA damage sensor enzyme poly (ADP-ribose) polymerase-1
(PARP1) and PARP1-mediated cell death and suppression of inflammatory gene expression.
See also
- Tricin synthase produces tricin or tricetin 3′,5′-dimethyl ether
- Tricetin 3′,4′,5′-O-trimethyltransferase
References