Peter Barnes (respiratory scientist)
Respiratory scientist and clinician | |
|---|---|
| Institutions | National Heart & Lung Institute Imperial College London Royal Brompton Hospital, London |
| Website | imperial |
Sir Peter John Barnes,
Imperial College and honorary consultant physician at the Royal Brompton Hospital London.[3] He is one of the most highly cited scientists in the world [4]
Early life
Barnes was born in
Leamington College. He won an open scholarship to St Catharine's College, Cambridge, where he graduated with a Bachelor of Arts in natural sciences (first-class honours) in 1969. He moved to the Clinical School University of Oxford, where he was a scholar and graduated BM, BCh
in 1972.
Medical career
After qualifying in medicine, he undertook clinical training at the
Imperial College and became an honorary consultant physician at Royal Brompton Hospital.[5]
In 1987 he was appointed to the established chair of thoracic medicine at NHLI and was head of respiratory medicine at
Imperial College until 2017.[6]
Barnes was knighted in the 2023 Birthday Honours for services to respiratory science.[7]
Research
His research initially focussed on adrenergic regulation of the airways, the role of endogenous
PI3K-δ. He also showed that theophylline was able to restore HDAC2 and reverse steroid resistance in COPD by selectively inhibiting oxidant-activated PI3Kδ.[14] He also pioneered the use of non-invasive markers to monitor inflammation in the airways and particularly exhaled nitric oxide, which is increased in asthma and reduced by steroid therapy.[15]
His research has had a major impact on current understanding of asthma and COPD mechanisms and how current therapies for these diseases work. This has identified several novel targets for therapy.
As a result of his research on steroid-resistance he co-founded (together with Garth Rapeport and Kazuhiro Ito) a
Imperial College called RespiVert in 2007,[16] which has discovered novel inhaled therapies that are now in clinical development for treatment of severe asthma and COPD since the company was acquired by Johnson & Johnson in 2010.[17]
Publications
Barnes is the author of over 1,500 publications in peer-reviewed journals[18] and is one of the most highly cited scientists in the world.[19] He has edited or co-edited over 50 books on asthma, COPD and respiratory pharmacology. His Web of Science h-index is over 200 with over 150,000 citations.
Family life
He married Olivia Harvard-Watts, a
psychotherapist, in 1976 and they have three sons: Adam (born 1978), Toby (born 1983) and Julian (born 1988).[20]
Honours and awards
- 1991 Linacre Lecture: Royal College of Physicians
- 1995 Dutch Medical Federation Annual Prize
- 1996 Amberson Lecture: American Thoracic Society
- 1997 MD Honoris Causa: University of Ferrara
- 1997 William Withering Lecture: Royal College of Physicians
- 1998 Founding Fellow: Academy of Medical Sciences
- 1998 Erasmus Lecture: Vrije Universiteit Brussel (University of Brussels)
- 1999 Sadoul Lecture: European Respiratory Society
- 2000 Manuel Albertal Memorial Lecture: American College of Chest Physicians
- 2001 MD Honoris Causa: University of Athens
- 2001 Poulson Prize: Norwegian Pharmacology Society
- 2002 College Medalist: American College of Chest Physicians
- 2008 MD Honoris Causa: University of Tampere
- 2007 Fellow of Royal Society (first respiratory researcher elected since Heny Hyde Salter in 1856)
- 2007 Gold Medal: British Thoracic Society
- 2009 Croonian Lecture: Royal College of Physicians[21]
- 2009 Senior Investigator: National Institute for Health and Care Research (NIHR)[22]
- 2010 MD Catholic University of Leuven
- 2011 Honorary Fellow St Catharine's College, Cambridge
- 2012 Master FCCP: American College of Chest Physicians
- 2012 Member Academia Europaea (European Academy)
- 2013 President: European Respiratory Society
- 2014 Doctorate Honoris Causa: University of Maastricht
- 2019-2023 President: British Association for Lung Research (BALR)
- 2020 Trudeau Medal [1]: American Thoracic Society
- 2020 Honorary Fellowship, British Pharmacology Society [2]
- 2022 The Imperial College Medal
References
- ^ "Peter Barnes". Google scholar. Archived from the original on 8 November 2017. Retrieved 7 December 2012.
- ^ "Curriculum vitae". 23 October 2023.
- ^ "Professor Peter Barnes". For healthcare professionals. Royal Brompton Hospital. Retrieved 7 December 2012.
- ^ "World Online Ranking of Best Medical Scientists".
- ^ "Professor Peter Barnes". For healthcare professionals. Royal Brompton Hospital. Retrieved 7 December 2012.
- ^ "Curriculum vitae". 23 October 2023.
- ^ "No. 64082". The London Gazette (Supplement). 17 June 2023. p. B2.
- PMID 6289123
- PMID 2418322
- PMID 9091804
- ^ Barnes P. J. "Chronic obstructive pulmonary disease". N Engl J Med 2000;343:269–280
- PMID 10958685
- PMID 15860753
- PMID 20224070
- PMID 7904001
- ^ "Home". respivert.com. Archived from the original on 4 November 2016. Retrieved 2 November 2012.
- ^ "J&J buys UK biotech RespiVert". June 2010.
- ^ http://www.imperial.ac.uk/people/p.j.barnes Publication list
- ^ "Home". highlycited.com.
- ^ "Who's Who home". www.ukwhoswho.com. Archived from the original on 6 December 2007.
- ^ "Croonian Lectures (Sadleir Trust)" (PDF). Royal College of Physicians. Archived from the original (PDF) on 11 February 2015.
- PMID 23919469.
External sources
- Curriculum Vitae
- Publications
- Citations Archived 8 November 2017 at the Wayback Machine
- COPD interview
- ScienceWatch interview on COPD research
