Prolactin modulator
| Prolactin modulator | |
|---|---|
D2 receptor (mainly) | |
| Legal status | |
| In Wikidata |
A prolactin modulator is a drug which affects the
pituitary hormone prolactin from the anterior pituitary gland. Prolactin inhibitors suppress and prolactin releasers induce the secretion of prolactin, respectively.[1][2]
Prolactin inhibitors
Prolactin inhibitors are mainly used to treat
GnRH analogues
are also able to inhibit the secretion of prolactin, though not nearly as robustly as D2 receptor agonists, and as such, they are not usually used as prolactin inhibitors.
Prolactin releasers
Whereas D2 receptor agonists suppress prolactin secretion, dopamine D2 receptor
serotonin precursors (e.g., tryptophan), serotonin reuptake inhibitors, serotonin releasing agents (e.g., fenfluramine, MDMA), monoamine oxidase inhibitors, and serotonin receptor agonists have also been associated with increases in prolactin levels.[5][6][7][8]
References
- ^ ISBN 978-1-60913-345-0.
- ^ ISBN 978-1-4496-9729-7.
- ISBN 978-1-351-78989-9.
- PMID 28273839.
- S2CID 6851723.
- PMID 18473017.
- PMID 9479619.
- S2CID 20016957.
External links
Media related to Prolactin modulators at Wikimedia Commons
