Ralph Walter Graystone Wyckoff

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Ralph Walter Graystone Wyckoff
BornAugust 9, 1897
DiedNovember 3, 1994 (1994-11-04) (aged 97)
NationalityAmerican
Alma materHobart College
Cornell University
Known forX-ray crystallography
Wyckoff positions
Scientific career
InstitutionsCarnegie Institution for Science
Rockefeller University
National Institutes of Health
University of Arizona
Doctoral advisorLouis Munroe Dennis
Other academic advisorsShoji Nishikawa

Ralph Walter Graystone Wyckoff, Sr. (August 9, 1897 – November 3, 1994), or simply Ralph Wyckoff, was an American chemist and pioneer of X-ray crystallography. He also made contributions to vaccine developments against epidemic typhus and other viruses.[1][2]

Biography

Wyckoff was the son of judge Abram Ralph Wyckoff and Ethel Agnes Catchpole. He studied at Hobart College, where he obtained a Bachelor of Science in 1916. He continued his studies at Cornell University, where he obtained his Ph.D. in 1919.[3] In 1916, he published his first scientific paper (of more than 400) at the age of nineteen in the Journal of the American Chemical Society. Under Shoji Nishikawa, he presented his thesis about the crystallographic resolution of the structures of NaNO3 and CsICl2 in 1919.

Wyckoff continued working in X-ray crystallography and wrote several books about the topic. Wyckoff's 1922 book, The Analytical Expression of the Results of the Theory of Space Groups, contained tables with the positional coordinates, both general and special, permitted by the symmetry elements. This book was the forerunner of International Tables for X-ray Crystallography, which first appeared in 1935. Both general and special positions are also called Wyckoff positions in his honor.

In 1927, Wyckoff moved to the

Ann Arbor, he invented a technique to take three-dimensional electron microscope images of bacteria using a "metal shadowing" technique.[6] Robley C. Williams worked with him to develop the technique. From 1946 to 1952, he researched macromolecules and viruses at the National Institutes of Health in Bethesda, Maryland. In 1948, he helped found the International Union of Crystallography and served as vice-president and president from 1951 to 1957.[5] In 1959, appalled by growing bureaucracy at the NIH, he took the job of professor of microbiology and physics at the University of Arizona
in Tucson, where he was forced to retire at the age of 80.

Wyckoff was married two times, the first time producing one son Ralph W.G. Wyckoff, Jr., the second marriage resulted in three daughters.[5]

Wyckoff was elected member of the

Electron Microscope Society of America in 1950.[7]

Bibliography

References

  1. . Retrieved 2024-05-19.
  2. ^ "RALPH W. G. WYCKOFF (1897 - 1994)". xray-exhibit.scs.illinois.edu. Retrieved 2024-05-19.
  3. ^ Asimov, Asimov's Biographical Encyclopedia of Science and Technology 2nd Revised edition
  4. ^ "Science: Rochester Paragon" Time Monday Feb 6, 1933. Accessed online at [1] on 3/23/2010
  5. ^ a b c d "Ralph W. G. Wyckoff 1897-1994," Acta Crystallogr. (1995). A51, 649-650. Accessed online at http://ww1.iucr.org/people/wyckoff.htm on 3/23/2010
  6. ^ "August 9 - Today in Science History - Scientists born on August 9th, died, and events".
  7. ^ "About MSA - Past Presidents". Microscopy Society of America. Retrieved 2024-12-24.