SNRPD3
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| Location (UCSC) | Chr 22: 24.56 – 24.58 Mb | Chr 10: 75.35 – 75.37 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Small nuclear ribonucleoprotein Sm D3 is a protein that in humans is encoded by the SNRPD3 gene.[5][6][7]
Function
The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis.[7]
Interactions
SNRPD3 has been shown to
interact
with:
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000100028 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020180 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 1701240.
- PMID 7527560.
- ^ a b "Entrez Gene: SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa".
- PMID 11101529.
- ^ PMID 11713266.
- PMID 10601333.
Further reading
- Liu Q, Fischer U, Wang F, Dreyfuss G (1997). "The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins". Cell. 90 (6): 1013–21. PMID 9323129.
- Fury MG, Zhang W, Christodoulopoulos I, Zieve GW (1998). "Multiple protein: protein interactions between the snRNP common core proteins". Exp. Cell Res. 237 (1): 63–9. PMID 9417867.
- Kambach C, Walke S, Young R, Avis JM, de la Fortelle E, Raker VA, Lührmann R, Li J, Nagai K (1999). "Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs". Cell. 96 (3): 375–87. PMID 10025403.
- Charroux B, Pellizzoni L, Perkinson RA, Shevchenko A, Mann M, Dreyfuss G (2000). "Gemin3: A Novel Dead Box Protein That Interacts with Smn, the Spinal Muscular Atrophy Gene Product, and Is a Component of Gems". J. Cell Biol. 147 (6): 1181–94. PMID 10601333.
- Charroux B, Pellizzoni L, Perkinson RA, Yong J, Shevchenko A, Mann M, Dreyfuss G (2000). "Gemin4: A Novel Component of the Smn Complex That Is Found in Both Gems and Nucleoli". J. Cell Biol. 148 (6): 1177–86. PMID 10725331.
- Brahms H, Raymackers J, Union A, de Keyser F, Meheus L, Lührmann R (2000). "The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies". J. Biol. Chem. 275 (22): 17122–9. PMID 10747894.
- Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI (2001). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23): 6569–81. PMID 11101529.
- Urlaub H, Raker VA, Kostka S, Lührmann R (2001). "Sm protein–Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure". EMBO J. 20 (1–2): 187–96. PMID 11226169.
- Friesen WJ, Massenet S, Paushkin S, Wyce A, Dreyfuss G (2001). "SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets". Mol. Cell. 7 (5): 1111–7. PMID 11389857.
- Friesen WJ, Paushkin S, Wyce A, Massenet S, Pesiridis GS, Van Duyne G, Rappsilber J, Mann M, Dreyfuss G (2001). "The Methylosome, a 20S Complex Containing JBP1 and pICln, Produces Dimethylarginine-Modified Sm Proteins". Mol. Cell. Biol. 21 (24): 8289–300. PMID 11713266.
- Gubitz AK, Mourelatos Z, Abel L, Rappsilber J, Mann M, Dreyfuss G (2002). "Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins". J. Biol. Chem. 277 (7): 5631–6. PMID 11714716.
- Meister G, Eggert C, Bühler D, Brahms H, Kambach C, Fischer U (2002). "Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln". Curr. Biol. 11 (24): 1990–4. S2CID 14742376.
- Pellizzoni L, Baccon J, Rappsilber J, Mann M, Dreyfuss G (2002). "Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component". J. Biol. Chem. 277 (9): 7540–5. PMID 11748230.
- Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, Mann M, Dreyfuss G (2002). "A novel WD repeat protein component of the methylosome binds Sm proteins". J. Biol. Chem. 277 (10): 8243–7. PMID 11756452.
- Fong YW, Zhou Q (2002). "Stimulatory effect of splicing factors on transcriptional elongation". Nature. 414 (6866): 929–33. S2CID 1518837.
- Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. PMID 11790298.
- Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39. PMID 11991638.
- Baccon J, Pellizzoni L, Rappsilber J, Mann M, Dreyfuss G (2002). "Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex". J. Biol. Chem. 277 (35): 31957–62. PMID 12065586.
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