Self-healing juvenile cutaneous mucinosis
| Self-healing juvenile cutaneous mucinosis | |
|---|---|
| Specialty | Dermatology  |
Self-healing juvenile cutaneous mucinosis is a skin condition caused by
Signs and symptoms
Combinations of nodules affecting the head, neck, and periarticular (particularly interphalangeal) joints, as well as linearly arranged ivory white papules over erythematous indurated skin, are examples of cutaneous manifestations.[2]
Myalgia, pyrexia, and muscle exhaustion are examples of mild inflammatory symptoms that typically appear at the same time as cutaneous lesions. More significantly, although they are uncommon, inflammatory symptoms can be connected to cutaneous lesions. These consist of transient hypertension, arthritic and joint pain, and severe hand and joint edema. Lesions lack extracutaneous involvement and are linked to absent to mild inflammatory symptoms like arthralgia, fever, weakness, and muscle tenderness. Additional symptoms include swelling in the hands, elbows, and knees, as well as excruciating polyarthritis or momentary hypertension.[3]
Causes
It is still unclear what initially cause the overproduction of mucin and the rise in fibroblast production.[4][5] Some authors speculated that it might be because of an infection or inflammation that stimulates the antigenic response continuously at the level of initial fibroblast and mucin production.[6][7]
Diagnosis
See also
- Lichen myxedematosus
- Skin lesion
References
Further reading
- Carder, K. Robin; Fitzpatrick, James E.; Weston, William L.; Morelli, Joseph G. (2003). "Self-Healing Juvenile Cutaneous Mucinosis". Pediatric Dermatology. 20 (1). Wiley: 35–39. S2CID 23338330.
- Kofler, Heinz; Lipsker, Dan; Maurer, Heiner; Burgdorf, Walter; Requena, Luis; Torrelo, Antonio; Zelger, Bernhard; Kutzner, Heinz; Müller, Hansgeorg (August 29, 2014). "Self-healing juvenile cutaneous mucinosis: challenging diagnosis and management". JDDG: Journal der Deutschen Dermatologischen Gesellschaft. 12 (9). Wiley: 815–817. S2CID 35875935.