Sergey Reformatsky
Sergey Nikolaevich Reformatsky | |
|---|---|
Alexander Mikhailovich Zaitsev, Wilhelm Ostwald |
Sergey Nikolaevich Reformatsky (Russian: Серге́й Никола́евич Реформа́тский; 1 April 1860 – 28 July 1934) was a Russian chemist.
Life
He was born as a son of a preacher in Borisoglebskoe, near
Work
In 1887 discovered the Reformatsky reaction, during which a zinc organic compound is the key component. The use of zinc in organic reactions was common at that time, but it was subsequently replaced by the more convenient magnesium. This was not possible for the reaction of α-chloro acids with ketones, because the magnesium based Grignard reagents are more reactive and lead to other products. This made the Reformatsky reaction a convenient way for the synthesis of β-hydroxy acids which were difficult to obtain with other methods.
References
Hofmann, K. A. (1935). "Sitzung am 8. April 1935". Berichte der Deutschen Chemischen Gesellschaft (A and B Series). 68 (5): A61–A71. .
- ^ "Reformatskii, Sergei Nikolaevich". Great Soviet Encyclopedia. 1979. Retrieved 2021-02-18.
