Small RNA
Small RNA (sRNA) are polymeric
Small RNA have been detected or sequenced using a range of techniques, including directly by MicroRNA sequencing on several sequencing platforms,[4][5][6] or indirectly through genome sequencing and analysis.[7] Identification of miRNAs has been evaluated in detecting human disease, such as breast cancer.[5] Peripheral blood mononuclear cell (PBMC) miRNA expression has been studied as potential biomarker for different neurological disorders such as Parkinson's disease,[8] Multiple sclerosis.[9] Evaluating small RNA is useful for certain kinds of study because its molecules "do not need to be fragmented prior to library preparation".[3]: 162
Types of small RNA include:
- microRNA (miRNA)[10]
- Piwi-interacting RNA (piRNA)
- small interfering RNA (siRNA)
- small nuclear RNA (snRNA), also commonly referred to as U-RNA
- small nucleolar RNA (snoRNA)
- small rDNA-derived RNA (srRNA)[11]
- tRNA fragment (tRF)[12]
- Y RNA-derived small RNA (ysRNA)[13]
In plants
The first known function in plants was discovered in mutants of
References
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