Theaflavin digallate
Names | |
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Systematic IUPAC name
3-Hydroxy-5-oxo-1,8-bis[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-2-yl]-5H-benzo[7]annulene-4,6-diyl bis(3,4,5-trihydroxybenzoate) | |
Other names
TFDG
TF-3 Theaflavin-3,3'-digallate | |
Identifiers | |
3D model (
JSmol ) |
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ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C43H32O20 | |
Molar mass | 868.709 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Theaflavin digallate (TFDG) is an antioxidant
natural phenol found in black tea, and a theaflavin
derivative.
Health
- TFDG is a scavenger of superoxide in vitro, even more so than EGCG.[1]
- Tea polyphenols including TFDG reduce angiogenesis,[medical citation needed] which is implicated in non-liquid cancers, an area of intense current research, by decreasing vascular endothelial growth factor production and receptor phosphorylation.[citation needed]
- TFDG inhibits activity of the enzyme 3CLpro in vitro.[2]
References
- PMID 10898615.
- PMID 15937562.)
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