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Source: Wikipedia, the free encyclopedia.

Barrier

In multi-cellular organisms, a barrier is structural entity between neighboring cells. Examples of barrier are blood–air barrier, Blood–brain barrier, Gastric mucosal barrier, Blood–testis barrier, Blood–ocular barrier, Blood–retinal barrier.

Structure

Generally, barrier consist of

tight junctions
.

Function

Barrier serves to prevent unregulated intercellular exchange of molecules.

Factors affecting barrier

Mutations affect barrier proteins leads to dysfunctional barrier.

Other barrier disruptors include


Diseases

Barrier dysfunction is related to numerous diseased conditions [3] [4] [5].

References