Virginia L. Miller
Virginia Miller | |
---|---|
Thesis | Analysis of the cholera toxin positive regulatory gene, toxR (1985) |
Virginia L. Miller is a
Education and career
Miller has a B.A. from the University of California, Santa Barbara (1979).[2] She earned her Ph.D. from Harvard University in 1985 where she worked on the expression of genes associated with Cholera toxin.[3] Following her Ph.D., she was a postdoc at Stanford University.[4] She moved to the University of California, Los Angeles in 1988 and earned tenure in 1994.[5] She moved to Washington University in St. Louis in 1996, and then to the University of North Carolina at Chapel Hill in 2008.[4] As of 2021, Miller is a professor of genetics, microbiology, and immunology at the University of North Carolina at Chapel Hill.[2]
Research
Miller is known for her research into bacterial pathogenesis, the factors leading to the onset of disease from specific species of bacteria.[6][7][8][9][10] Her early research examined the synthesis of the cholera toxin by Vibrio cholerae[11][12] and identified environmental signals that lead V. cholerae to express the proteins needed to make the cholera toxin.[13] She went on to examine the mechanisms by which another bacteria pathogen - Yersinia pestis - enters cells[14] and cause disease.[15] She has also worked on how Salmonella[16][17] and Klebsiella pneumoniae[18][19] cause disease.In brief, she mostly worked in the areas of Microbiology (69.74%), Yersinia enterocolitica (51.32%) and Virulence (48.03%).[20]
Awards and honors
In 1989, Miller was named a
Selected publications
- Miller, Virginia L.; Taylor, Ronald K.; Mekalanos, John J. (1987-01-30). "Cholera toxin transcriptional activator ToxR is a transmembrane DNA binding protein". Cell. 48 (2): 271–279. S2CID 28576010.
- Miller, V L; Mekalanos, J J (1988-06-01). "A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR". Journal of Bacteriology. 170 (6): 2575–2583. PMID 2836362.
- Taylor, R. K.; Miller, V. L.; Furlong, D. B.; Mekalanos, J. J. (1987-05-01). "Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin". Proceedings of the National Academy of Sciences. 84 (9): 2833–2837. PMID 2883655.
References
- ^ a b "Virginia L. Miller, PhD". PEW Trusts - Biomedical Scholars (1989). Retrieved 2022-03-16.
- ^ a b "Virginia Miller, PhD". Institute for Global Health and Infectious Diseases. Retrieved 2021-12-04.
- OCLC 17572198.
- ^ a b "Virginia Miller, Ph.D." ASM.org. Retrieved 2021-11-30.
- ^ a b "Miller biographical sketch" (PDF). 2014-02-23. Archived (PDF) from the original on 2014-02-23. Retrieved 2021-12-04.
- PMID 10572314.
- PMID 7591144.
- S2CID 25748196.
- PMID 8932305.
- PMID 21115720.
- PMID 6374658.
- S2CID 28576010.
- PMID 2836362.
- PMID 2833444.
- PMID 2642465.
- PMID 9537377.
- PMID 10398673.
- S2CID 44666800.
- PMID 17220312.
- ^ "Virginia L. Miller: H-index & Awards - Academic Profile". Research.com. Retrieved 2022-07-29.
- ^ "American Academy of Microbiology fellows". Retrieved December 3, 2021.