White (mutation)
white | |||||||
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UniProt P10090 | | ||||||
Other data | |||||||
Chromosome | X: 2.79 - 2.8 Mb | ||||||
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white, abbreviated w, was the first
Function
The protein coded by the white gene functions as an
Effects mutation
Drosophila melanogaster with the white eye mutation typically have shorter life spans than wildtype Drosophila. They also experience many neurological deficiencies in addition to eye defects. Some of the deficiencies that they experience includes difficulty in mobility, and a low stress tolerance. Drosophila melanogaster with the white eye mutation often experience an increased sensitivity to light and a decrease in visual acuity. They have significantly less in the number of synaptic vesicles of photoreceptors.
White eye mutants of Drosophila melanogaster experience a lower rate of reproduction than their wildtype counterparts because they experience a reduced rate of sexual arousal during daylight.[6] Ectopic expression of white+ induces male-male courtship in Drosophila.[7] White+ controls the copulation success in Drosophila melanogaster.[8]
Notes and references
- PMID 17759620.
- ^ As the field of genetics developed, names for genes were italicized, and for Drosophila the normal (wild type) allele was given a + modifier, for example w+. Names of commonly used mutations were shortened, and since white was the first named, it was shortened to a single letter.
- ^ Morgan TH (1919). The physical basis of heredity. Philadelphia: J.B. Lippincott Company.
- PMID 10407069.
- .
- PMID 29354028.
- PMID 7777542.
- PMID 28794482.