Alphapolyomavirus
| Alphapolyomavirus | |
|---|---|
| |
| Alphapolyomavirus model with a non-enveloped capsid and a T = 7d icosahedral symmetry at a 50 nm diameter scale. | |
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Monodnaviria |
| Kingdom: | Shotokuvirae |
| Phylum: | Cossaviricota |
| Class: | Papovaviricetes |
| Order: | Sepolyvirales |
| Family: | Polyomaviridae |
| Genus: | Alphapolyomavirus |
Alphapolyomavirus is one of eight
dsDNA viruses in the polyomaviridae family.[1][2] Member viruses primarily infect humans and other mammals.[3] Transmission of the virus in humans is primarily spread via direct contact with parents or other high-contact individuals as children.[4][5]
The primary alphapolyomavirus that is of clinical significance to humans is Merkel cell polyomavirus (Human polyomavirus 5, MCV, or MCPyV). The apparent oncogenicity of MCPyV[6] similar to other cancer-causing viruses such as HPV, Epstein-Barr virus, and Hepatitis C virus[7] is a main area of research for the scientific community.
References
- ^ taxonomy. "Taxonomy browser (Polyomaviridae)". www.ncbi.nlm.nih.gov. Retrieved 2024-03-19.
- ^ "Alphapolyomavirus ~ ViralZone". viralzone.expasy.org. Retrieved 2024-03-19.
- ^ "Genus: Alphapolyomavirus | ICTV". ictv.global. Retrieved 2024-03-19.
- PMID 7650165.
- PMID 20060360.
- PMID 23217622.
- ^ "Gale – Product Login". galeapps.gale.com. Retrieved 2024-03-19.