Cornea plana 2
| Cornea plana 2 | |
|---|---|
| Other names | Autosomal recessive Cornea plana, CNA2. |
autosomal recessive manner. | |
| Specialty | Medical genetics  |
Cornea plana 2 (CNA2) is a
Signs and symptoms
Cornea plana commonly presents as a flat cornea, early-onset arcus lipoides, low anterior chamber depth, and an indistinct border between the sclera and cornea due to a decreased angle between the two.[2] Although a small corneal diameter is anticipated, measuring it can be challenging because the scleral tissue overlaps the cornea by a few millimeters. In the patients who have cornea plana, the anterior chamber depth has been found to vary from 0.8 to 2.1 mm.[5]
Moreover, high
Diagnosis
Clinical presentation, keratometry,[7] pachymetry, and endothelial imaging are used to make the diagnosis.[8]
Since the decreased refraction in the autosomal recessive form is more severe than in the autosomal dominant form, corneal refraction measurements can be used to differentiate between CNA1 and CNA2.[5]
Histology is distinguished by
See also
References
Further reading
- Khan, Arif O. (2012). "Cornea Plana". Genetic Diseases of the Eye. Oxford University Press. pp. 85–91. ISBN 978-0-19-532614-7.
- Coleman, Michael (2018). "Cornea Plana". Encyclopedia of Ophthalmology. Berlin, Heidelberg: Springer Berlin Heidelberg. pp. 513–514. ISBN 978-3-540-68292-9.