Fixed drug reaction
(Redirected from
Fixed drug eruption
)Fixed drug reaction | |
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Other names | Drug eruption |
Fixed drug eruption caused by phenolphtalein. | |
Specialty | Dermatology |
Fixed drug reactions are common and so named because they recur at the same site with each exposure to a particular medication.[1] Medications inducing fixed drug eruptions are usually those taken intermittently.[1]
Signs and symptoms
A painful and itchy reddish/purple patch of skin that occurs in the same location with repeated exposures to the causative drug is the classic presentation of a fixed drug reaction. The lips, genitals, and hands are often involved.
Cause
Medications that are commonly implicated as a cause of fixed drug eruptions include the following:
- Cetirizine
- Ciprofloxacin
- Clarithromycin
- Cotrimoxazole
- Doxycycline
- Fluconazole
- )
- Phenytoin
- Pseudoephedrine[2]
- Trimethoprim
See also
- Drug eruption
- List of cutaneous conditions
- List of human leukocyte antigen alleles associated with cutaneous conditions
- Stevens–Johnson syndrome
References
- ^ ISBN 978-0-7216-2921-6.
- PMID 9564979.