Formononetin

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Formononetin
Formononetin molecule
Names
IUPAC name
7-Hydroxy-4′-methoxyisoflavone
Systematic IUPAC name
7-Hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one
Other names
Biochanin B
Formononetol
4'-O-methyldaidzein
Identifiers
3D model (
JSmol
)
237979
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard
 100.006.931 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3 checkY
    Key: HKQYGTCOTHHOMP-UHFFFAOYSA-N checkY
  • InChI=1/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3
    Key: HKQYGTCOTHHOMP-UHFFFAOYAJ
SMILES
  • O=C\1c3c(O/C=C/1c2ccc(OC)cc2)cc(O)cc3
Properties
C16H12O4
Molar mass 268.26 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

Formononetin is an

O-methylated isoflavone
.

Natural occurrences

Formononetin is found in a number of plants and herbs such as

soy and many others, as the free aglycone or in form of its glucoside ononin.[2]

It can also be found in Maackia amurensis cell cultures.[3]

Pharmacodynamics

Formononetin promotes angiogenesis.[4] It is also involved in expressing the gene and proteins that are needed to make IgE.[5]

Derivatives

Ononin is the 7-O-β-D-glucopyranoside of formononetin.[6]

References

  1. S2CID 206495959
    .
  2. ^ "Iowa State University Database on the Isoflavone Content of Foods, Release 1.3". USDA. 2002. Archived from the original on 2012-11-02. Retrieved 2011-02-13.
  3. PMID 10925005
    .
  4. PMID 26568398
    .
  5. ^ "This plant-based compound could finally cure food allergies". ZME Science. 2022-04-01. Retrieved 2022-04-04.
  6. ISBN 9057022850
    .


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