Giulio Bizzozero
Giulio Bizzozero | |
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histography, platelet | |
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Giulio Bizzozero (Italian pronunciation: [ˈdʒuːljo bidˈdzɔddzero]; 20 March 1846 – 8 April 1901) was an Italian doctor and medical researcher. He was a pioneer of histology and is credited with the coining of the term platelets and identifying their function in coagulation.
Background
Bizzozero was born in
In 1872, at the age of 26, he moved to the University of Turin, and founded the Institute of General Pathology. While at Turin he worked to improve hygiene and water supply. Among the physicians who worked and studied in his laboratory at Turin were Edoardo Bassini (1844-1924) and Carlo Forlanini (1847-1918).[1]
In April 1901, he died of
Achievements
Bizzozero was one of the pioneers of histology, and, more generally, the use of the microscope in medical research. He is known for his early description of Helicobacter pylori (1892), the bacteria that is responsible for peptic ulcer disease (although this fact was not generally accepted until the 1990s).[2]
In 1869 he noted the value of blood transfusions in treating anemia. In 1881 he described platelets as a third element in blood after the erythrocytes and leucocytes. Platelets had been described by Max Schultze in 1865 but Bizzozero identified their function. He called them petit plaques (Italian), plaquettes (French) and Blutplattchenin (German). He demonstrated their role in clotting through aggregation and clumping with the formation of thread like structures now known as fibrin.[3][4][5]
Other significant work by Bizzozero included research of
See also
References
- ^ Bizzozero, Giulio - Universalium (biographical information)
- ^ Helicobacter pylori and the Bacterial Theory of Ulcers by Debra Ann Meuler Department of Natural Sciences Cardinal Stritch University
- PMID 17383722.
- S2CID 22705707.
- PMID 17383722.
- ^ Giulio Bizzozero: a pioneer of cell biology Archived 2016-03-05 at the Wayback Machine by Paolo Mazzarello, Alessandro L. Calligaro and Alberto Calligaro
- PMC 2742091, The Desmosome
Sources
- Figura, Natale; Laura Bianciardi (2002). "Helicobacters were discovered in Italy in 1892: An episode in the scientific life of an eclectic pathologist, Giulio Bizzozero". In Barry Marshall (ed.). Helicobacter Pioneers: Firsthand Accounts from the Scientists Who Discovered Helicobacters. Victoria, Australia: Blackwell Science Asia. pp. 1–13. ISBN 0-86793-035-7.
- Vigliani, R. (August 2002). "Giulio Bizzozero: Remenbrance 100 years after his death". Pathologica. 94 (4): 206–215. PMID 12325420.
- Brewer, DB (2006). "Max Schultze (1865), G. Bizzozero (1882) and the discovery of the platelet". Br J Haematol. 133 (3): 251–8. S2CID 19334121.