Löfgren syndrome
Löfgren syndrome | |
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hilar lymphadenopathy . (Note: Other symptoms are classically not present in Löfgren syndrome.) |
Löfgren syndrome is a type of acute
Signs and symptoms
It is characterized by enlargement of the
Löfgren syndrome consists of the triad of erythema nodosum, bilateral hilar lymphadenopathy on chest radiograph, and joint pain.[citation needed]
Genetics
Recent studies have demonstrated that the HLA-DRB1*03 is strongly associated with Löfgren syndrome.[6]
Diagnosis
The triad of erythema nodosum, acute arthritis, and bilateral hilar lymphadenopathy is highly specific (>95%) for the diagnosis of Löfgren syndrome. When the triad is present, further testing with additional imaging and laboratory testing is unnecessary.[citation needed]
Treatment
NSAIDs (nonsteroidal anti-inflammatory drugs) are the usual recommended treatment for Löfgren syndrome.[7] Colchicine or low-dose prednisone may also be used.
Prognosis
Löfgren syndrome is associated with a good prognosis, with > 90% of patients experiencing disease resolution within 2 years. In contrast, patients with the disfiguring skin condition lupus pernio or cardiac or neurologic involvement rarely experience disease remission.[citation needed]
See also
- List of cutaneous conditions
- Sarcoidosis
References
- PMID 16755100.
- ^ ISBN 978-1405183239.
- PMID 13079656.
- ^ Sven Halvar Löfgren biography
- PMID 17023727.
- PMID 18996998.
- PMID 36788849.