Lucey–Driscoll syndrome
| Lucey–Driscoll syndrome | |
|---|---|
| Other names | Transient familial neonatal hyperbilirubinemia |
 | |
| Lucey–Driscoll syndrome has an autosomal recessive pattern of inheritance. | |
| Specialty | DiseasesDB = 32677 |
Lucey–Driscoll syndrome is an
hyperbilirubinemia
.
Signs and symptoms
![[icon]](/File:Wiki_letter_w_cropped.svg){kind=small} | This section is empty. You can help by adding to it. (March 2022) |
Cause
The common cause is congenital, but it can also be caused by maternal
newborn
. It is different from breast feeding-associated jaundice (breast-fed infants have higher bilirubin levels than formula-fed ones).
Genetics
A defect in the
UGT1A1-gene, also linked to Crigler–Najjar syndrome and Gilbert's syndrome
, is responsible for the congenital form of Lucey–Driscoll syndrome.
Diagnosis
| This section is empty. You can help by adding to it. (August 2017) |
Treatment
Treatment is as per
phototherapy and exchange transfusions. If left untreated, Lucey-Driscoll syndrome may lead to seizures, kernicterus, and even death.[2]
Once treated, most patients will have no additional complications.[2]
References
- ^ "Lucey-Driscoll syndrome | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Retrieved 2017-08-27.
- ^ a b "Lucey-Driscoll syndrome | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program".
External links
- Online Mendelian Inheritance in Man (OMIM): 237900 - transient familial neonatal hyperbilirubinemia, breast feeding jaundice included
 | This genetic disorder article is a stub. You can help Wikipedia by expanding it. |