Nonbacterial thrombotic endocarditis
| Nonbacterial thrombotic endocarditis | |
|---|---|
| Specialty | Cardiology  |
| Treatment | Anticoagulation |
Nonbacterial thrombotic endocarditis (NBTE) is a form of endocarditis in which small sterile vegetations are deposited on the valve leaflets. Formerly known as marantic endocarditis, which comes from the Greek marantikos, meaning "wasting away".[1] The term "marantic endocarditis" is still sometimes used to emphasize the association with a wasting state[2] such as cancer.[3]
Risk factors
Marantic vegetations are often associated with previous rheumatic fever. Other risk factors include:[citation needed]
- hypercoagulable states
- malignant cancers, especially mucin-producing adenocarcinomas (most commonly associated with pancreatic adenocarcinomas)
- Libman-Sacks endocarditis
- catheters)
Valve predilection
The disease affects the valves with following predilection: mitral valve > aortic valve > tricuspid valve > pulmonary valve[4]
Histopathology
Grossly, vegetations form along lines of valve closure and are generally symmetric with a smooth or
]Diagnosis
Due to the non-invasive nature of NBTE, clinical examination may or may not reveal a new
References
- ^ Neurological Sequelae of Infectious Endocarditis at eMedicine
- ^ "Noninfective Endocarditis: Endocarditis: Merck Manual Professional". Retrieved 2008-12-22.
- ^ "Marantic endocarditis". Online Medical Dictionary. Retrieved 2008-12-22.
- ^ "UpToDate".
- ^ "nonbacterial thrombotic endocarditis" at Dorland's Medical Dictionary