Quisqualamine

Quisqualamine
Names
	IUPAC name 2-(2-aminoethyl)-1,2,4-oxadiazolidine-3,5-dione
Identifiers
CAS Number	68373-11-5 ;
3D model ( JSmol)	Interactive image;
ChemSpider	2342291;
PubChem CID	3085372;
UNII	PJ4RW6N4EA ;
CompTox Dashboard (EPA)	DTXSID60218503 ;
	InChI InChI=1S/C4H7N3O3/c5-1-2-7-3(8)6-4(9)10-7/h1-2,5H2,(H,6,8,9) Key: LIPCXBVXQUFCSC-UHFFFAOYSA-N; InChI=1/C4H7N3O3/c5-1-2-7-3(8)6-4(9)10-7/h1-2,5H2,(H,6,8,9) Key: LIPCXBVXQUFCSC-UHFFFAOYAA;
	SMILES O=C1NC(=O)ON1CCN;
Properties
Chemical formula	C4H7N3O3
Molar mass	145.118 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Quisqualamine is the

agonist of the GABA_A receptor and also to a lesser extent as an agonist of the glycine receptor, due to the facts that its actions are inhibited in vitro by GABA_A antagonists like bicuculline and picrotoxin and by the glycine antagonist strychnine, respectively.^[1]^[2]^[3] Mg²⁺ and DL-AP5, NMDA receptor blockers, CNQX, an antagonist of both the AMPA and kainate receptors, and 2-hydroxysaclofen, a GABA_B receptor antagonist, do not affect quisqualamine's actions in vitro, suggesting that it does not directly affect the ionotropic glutamate receptors or the GABA_B receptor in any way.^[2] Whether it binds to and acts upon any of the metabotropic glutamate receptors