Reptilase time

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Reptilase time
Purposeblood test used to detect deficiency or abnormalities in fibrinogen

Reptilase time (RT) is a blood test used to detect deficiency or abnormalities in fibrinogen,[1][2] especially in cases of heparin contamination.

fibrinopeptide B, in its cleavage of fibrinogen.[citation needed
]

Causes of prolonged thrombin time[3]
Reptilase time Cause Further workup indicated
Normal Heparin, hirudin, or direct thrombin inhibitor Human TT and/or heparin assays
Prolonged Hypo- or afibrinogenemia Fibrinogen quantification
Dysfibrinogenemia Fibrinogen activity assay
Fibrin(ogen) split products (FSP) FSP or D-dimer quantification

References

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  3. ^ "Test ID: RTSC. Reptilase Time, Plasma". Mayo Clinic laboratories. Retrieved 2021-02-25.