Sinovac Biotech
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Hanyu Pinyin | Kē Xìng Kònggǔ Shēngwù Jìshù Yǒuxiàn Gōngsī |
Sinovac Biotech Ltd. (
Vaccines
Sinovac's commercialized vaccines include
COVID-19 vaccine development
CoronaVac is an inactivated virus COVID-19 vaccine developed by Sinovac.[6] It has been in Phase III clinical trials in Brazil,[7] Chile,[8] Indonesia,[9] Philippines,[10] and Turkey.[11]
It relies on traditional technology similar to the Sinopharm BIBP vaccine and Covaxin, otherwise known as inactivated-virus COVID-19 vaccines in Phase III trials.[12] CoronaVac does not need to be frozen, and both the vaccine and raw material for formulating the new doses could be transported and refrigerated at 2–8 °C (36–46 °F), temperatures at which flu vaccines are kept.[13]
A real-world study of ten millions of Chileans who received CoronaVac found it 66% effective against symptomatic COVID-19, 88% against hospitalization, 90% against ICU admissions, and 86% against deaths.[14] In Brazil, after 75% of the population in Serrana, São Paulo received CoronaVac, preliminary results show deaths fell by 95%, hospitalizations by 86%, and symptomatic cases by 80%.[15][16] In Indonesia, real world data from 128,290 healthcare workers showed 94% protection against symptomatic infection by the vaccine, beating results in clinical trials.[17]
Phase III results from Turkey published in The Lancet showed an efficacy of 84% based on 10,218 participants in the trials.[18][19] Phase III results from Brazil previously showed 50.7% efficacy at preventing symptomatic infections and 83.7% effective in preventing mild cases needing treatment. Efficacy against symptomatic infections increased to 62.3% with an interval of 21 days or more between the doses.[20]
CoronaVac is being used in vaccination campaigns in various countries in Asia,[21][22][23] South America,[24][25][26] North America,[27][28][29] and Europe.[30][31][32] By April 2021, Sinovac had a production capacity of two billion doses a year[33] and had delivered 600 million total doses.[34] It is currently being manufactured at several facilities in China,[33] Brazil,[35] and Egypt.[36] On 1 June 2021, the World Health Organization (WHO) validated the vaccine for emergency use.[37][38][39] Sinovac has signed purchase agreements for 380 million doses from COVAX.[40]
See also
- CanSino Biologics
- Sinopharm
References
- ^ "China's Vaccine Front-Runner Aims to Beat Covid the Old-Fashioned Way". Bloomberg. 24 August 2020.
- ^ Submission Proof - tv479639
- ^ from the original on December 4, 2020. Retrieved 2020-12-06.
- ^ Levine, Matt (May 22, 2020). "A Vaccine With a Poison Pill". Bloomberg News. Archived from the original on June 21, 2020. Retrieved December 6, 2020.
- ^ "Vaccines". sinovac.com. Archived from the original on 26 September 2021. Retrieved 1 September 2021.
- ^ Nidhi Parekh (22 July 2020). "CoronaVac: A COVID-19 Vaccine Made From Inactivated SARS-CoV-2 Virus". Retrieved 25 July 2020.
- ^ "New coronavirus vaccine trials start in Brazil". AP News. 21 July 2020. Retrieved 2020-10-07.
- ^ "Chile initiates clinical study for COVID-19 vaccine". Chile Reports. 4 August 2020. Retrieved 2020-10-07.
- ^ "248 volunteers have received Sinovac vaccine injections in Bandung". Antara News. 30 August 2020. Retrieved 2020-10-07.
- ^ "DOH eyes 5 hospitals for Sinovac vaccine Phase 3 clinical trial". PTV News. 16 September 2020. Retrieved 2020-10-07.
- ^ "Turkey begins phase three trials of Chinese Covid-19 vaccine". TRT World News. 1 September 2020. Retrieved 2020-10-07.
- ISSN 0362-4331. Retrieved 2021-02-12.
- ^ "CoronaVac: Doses will come from China on nine flights and can..." AlKhaleej Today (in Arabic). 2020-11-01. Retrieved 2021-02-12.
- S2CID 235766915.
- ^ Savarese M (2021-06-01). "Sinovac vaccine restores a Brazilian city to near normal". CTV News. Retrieved 2021-06-02.
- ISSN 0099-9660. Retrieved 2021-06-02.
- ^ "China Sinovac Shot Seen Highly Effective in Real World Study". Bloomberg News. 3 June 2023. Retrieved 3 June 2023.
- S2CID 235770533.
- ^ Evidence Assessment: Sinovac/CoronaVac COVID-19 vaccine (PDF) (Presentation). World Health Organization. 29 April 2021. Retrieved 10 July 2021.
- ^ Costa A (2021-04-11). "Estudo clínico que comprova maior eficácia da Coronavac é enviado para Lancet" [Clinical study proving greater efficacy of Coronavac is submitted to The Lancet]. CNN Brasil (in Portuguese). São Paulo. Retrieved 2021-04-12.
- ^ TARIGAN, EDNA; MILKO, VICTORIA (13 January 2021). "Indonesia starts mass COVID vaccinations over vast territory". Associated Press. Retrieved 15 January 2021.
- ^ "Thailand Kicks Off Covid-19 Vaccine Program With Sinovac Shots". Bloomberg.com. Retrieved 28 February 2021.
- ^ "China approves Sinovac vaccines for general public use". South China Morning Post. 6 February 2021. Retrieved 6 February 2021.
- ^ Rochabrun, Marcelo. "Brazil health ministry says plans to order 30 million more Coronavac doses | The Chronicle Herald". www.thechronicleherald.ca. Retrieved 26 February 2021.
- ^ Miranda, Natalia A. Ramos (28 January 2021). "Chile receives two million-dose first delivery of Sinovac COVID-19 vaccine". Reuters. Retrieved 30 January 2021.
- ^ "BNamericas - Uruguay prepares to launch COVID-19 vaccinat..." BNamericas.com. Retrieved 1 March 2021.
- ^ "Venustiano Carranza next up for Covid vaccination in Mexico City". Mexico News Daily. 2021-03-15. Retrieved 2021-03-16.
- ^ "Anticovid vaccines run out as Dominican Republic awaits arrival of more doses". Dominican Today. Retrieved 2021-03-10.
- ^ "Llegan a El Salvador un millón de dosis de la vacuna china CoronaVac contra el covid-19 de la farmacéutica Sinovac". Noticias de El Salvador - La Prensa Gráfica | Informate con la verdad (in European Spanish). Retrieved 2021-03-28.
- ^ "Turkey aims to vaccinate 60 percent of population: Minister – Turkey News". Hürriyet Daily News. 11 February 2021. Retrieved 12 February 2021.
- ^ "Vaccination with CoronaVac launched in Ukraine on April 13 – Health minister". www.unian.info. Retrieved 2021-04-15.
- ^ Semini, Llazar. "Albania starts mass COVID vaccinations before tourist season". ABC News. Retrieved 2021-03-28.
- ^ a b Liu, Roxanne (2021-04-02). "China Sinovac says it reached two billion doses annual capacity for COVID-19 vaccine". Reuters. Retrieved 2021-04-02.
- ^ Nebehay, Stephanie (2021-06-01). "WHO approves Sinovac COVID vaccine, the second Chinese-made dose listed". Reuters. Geneva. Retrieved 2021-06-01.
- ^ Mano A, Simões (10 December 2020). "Chinese vaccine draws demand across Latin America, say Brazilian officials". Reuters. Archived from the original on 10 December 2020. Retrieved 10 December 2020.
- ^ "Egypt to produce up to 80 million Sinovac vaccine doses annually". Arab News. 2021-04-08. Retrieved 2021-04-08.
- ^ Nebehay S (2021-06-01). "WHO approves Sinovac COVID vaccine, the second Chinese-made dose listed". Reuters. Geneva. Retrieved 2021-06-01.
- ^ "WHO recommendation Sinovac COVID-19 vaccine (Vero Cell [Inactivated]) – CoronaVac". World Health Organization (WHO). 1 May 2021. Archived from the original on 2 June 2021. Retrieved 1 June 2021.
- ^ "WHO validates Sinovac COVID-19 vaccine for emergency use and issues interim policy recommendations". World Health Organization (WHO) (Press release). Retrieved 1 June 2021.
- ^ "Chinese drugmakers agree to supply more than half a billion vaccines to COVAX". Reuters. 2021-07-12. Retrieved 2021-07-13.
External links
- Official website
- Business data for Sinovac Biotech: