Sten Grillner

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Sten Grillner
Karolinska Institutet

Sten Grillner (born 14 June 1941,

neuronal circuits in the spine help control rhythmic movements, such as those needed for locomotion. He is the current secretary general of the International Brain Research Organization (IBRO) and president of the Federation of European Neuroscience Societies (FENS). For his work, in 2008 he was awarded the $1 million Kavli Prize for deciphering the basic mechanisms which govern the development and functioning of the networks of cells in the brain and spinal cord. This prize distinguish the recipient from the Nobel prizes in basic medical sciences.[2]

Notable neuroscientists like

Nobel laureates in physiology or medicine named Grillner's work on the workings of complex neurocircuitry extremely important and this progress in understanding motor systems, the cognitive role in motor systems, is a brilliant advance and has revolutionized our understanding of how the nervous system is wired.[3]

Prof. Grillner studied at the medical faculty in

Bristol-Myers Squibb Award in 1993 and the Reeve–Irvine award in 2002. He was the co-recipient of the 2005 SfN Ralph Gerard Prize, highest recognition conferred by Society for Neuroscience and he was a co-recipient, with Thomas Jessell and Pasko Rakic, of the inaugural Kavli Prize
for Neuroscience in 2008.

Research

His research has focused on the extraordinary capability of the brain to control movement. Early on he demonstrated that networks within the mammalian spinal cord can produce the detailed motor pattern of locomotion involving the coordination of hundreds of different muscles. In a paper published in 1987, he and James Buchanan provided a putative network scheme of interacting interneurons in the lamprey spinal cord, a model vertebrate system.[4] The level of detail gained in this work is unique in that it has allowed changes in behaviour to be related to changes occurring at the cellular and network level. His later work is directed towards understanding the forebrain mechanisms underlying selection of behavior, and has shown that the organization of the basal ganglia, dopamine system, habenulae and pallium is evolutionary conserved in considerable detail over more than 500 million years.

He is a member of the Norwegian Academy of Science and Letters.[5]

References

  1. ^ Who's Who in Medicine and Healthcare 1999/2000, Marquis Who's Who 1998
  2. ^ "Gruppe 7: Kavali Prize" (in Norwegian). Norwegian Academy of Science and Letters. Archived from the original on 2 December 2010. Retrieved 7 October 2010.
  3. ^ "Interview with 2000 Nobel laureate Dr. Erick Kandel". Retrieved 6 April 2006.
  4. PMID 3563512
    .
  5. ^ "Gruppe 7: Medisinske fag" (in Norwegian). Norwegian Academy of Science and Letters. Retrieved 7 October 2010.

External links

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