Benjamin Cravatt III

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Benjamin F. Cravatt III
Born (1970-04-13) April 13, 1970 (age 54)
Houston, Texas, USA
EducationStanford University B.S. and B.A. (1992)
The Scripps Research Institute
Vividion Therapeutics
ActivX Biosciences
Abide Therapeutics
Doctoral advisors

Benjamin Franklin Cravatt III is a professor in the Department of Chemistry at

Searle Scholar
.

Early life and education

His father was a dentist and his mother a dental hygienist, both of whom instilled in Cravatt an interest in biology as a child.[1]

Cravatt entered

The Scripps Research Institute in 1996,[1] where he worked under the joint supervision of Dale L. Boger and Richard Lerner
.

Research

His early contributions to the

fatty acid amide hydrolase (FAAH),[1] as well as the isolation of the novel soporific compound oleamide from cerebrospinal fluid.[4][5]

Cravatt and colleagues pioneered the

activity-based protein profiling (ABPP) chemical proteomic technology, which they used in 2010 to elucidate certain global proteomic features of cysteine proteases.[1] Cravatt's lab has since combined the ABPP technology with metabolomics.[1]

Awards and professional service

Among the awards that Cravatt has received are the

TR100 Award in 2002, the Eli Lilly Award in Biological Chemistry in 2004, the ASBMB-Merck Award in 2014 and the Sato Memorial Award in 2015.[1] Cravatt also received an NCI MERIT grant in 2009.[1] In 2022 he was awarded the Wolf Prize in Chemistry.[6]

Cravatt is a co-founder of Vividion Therapeutics, Abide Therapeutics and ActivX Biosciences. He formerly served as an Associate Editor for the Journal of the American Chemical Society and Chemical Science.

See also

  • Fatty acid amide hydrolase
  • Activity-based protein profiling
  • Chemoproteomics

References

  1. ^
    PMID 26811454
    .
  2. ^ "National Academy of Sciences Members and Foreign Associates Elected" (Press release). United States: National Academy of Sciences. 29 April 2014. Archived from the original on 18 August 2015. Retrieved 2016-12-31. Cravatt, Benjamin F.; professor and chair, department of chemical physiology, The Scripps Research Institute, La Jolla, Calif.
  3. doi:10.1016/j.cbpa.2006.12.029
    .
  4. S2CID 4288981
    .
  5. PMID 7770779
    .
  6. ^ Wolf Prize in Chemistry 2022

External links

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