Harvey Itano

Source: Wikipedia, the free encyclopedia.
Harvey Akio Itano
St. Louis University, California Institute of Technology
Known forDifferentiating normal and sickle cell hemoglobins
AwardsEli Lilly Award in Biological Chemistry (1954)
Martin Luther King Jr. Medical Achievement Award
Scientific career
FieldsBiochemistry
Institutions
ThesisI. Contributions to the Study of Sickle Cell Hemoglobin II. A Rapid Diagnostic Test for Sickle Cell Anemia (1950)
Doctoral advisorLinus Pauling

Harvey Akio Itano (

protein electrophoresis, though the use of electrophoresis to separate hemoglobin variants had been pioneered by Maud Menten and collaborators some years earlier.[3]

In 1979, Itano became the first

United States National Academy of Sciences (in the Genetics section). Itano was an emeritus professor of pathology at the University of California, San Diego.[4] In 2010, Itano died of complications from Parkinson's disease in La Jolla, California.[5]

Early life

Recent UC Berkeley valedictorian Itano in an internment camp.

Itano was born in

St. Louis University medical school, earning his M.D. in 1945. He then went to graduate school at the California Institute of Technology, where he received doctorates in chemistry and physics in 1950.[8]

Research

While at Caltech, Itano joined the lab of

peptide sequence,[12] which by 1958 he determined to be a valine in the sickle cell mutant hemoglobin in place of glutamic acid in normal hemoglobin A.[13]

Itano's subsequent work brought the new field of "molecular medicine" to other genetic and blood diseases. In 1954, he won the

Eli Lilly Award in Biological Chemistry, and in 1972 he won the Martin Luther King Jr. Medical Achievement Award, recognizing his sickle cell work.[10]

References

  1. ^ Transcription from Japanese version of the article.
  2. S2CID 31674765
    .
  3. doi:10.1016/S0021-9258(18)51237-0
    .
  4. ^ a b K. W. Lee. "Remarkable Parents Who Raised Remarkable Family." Sacramento Union, June 25, 1979. Reprint from the Nichi Bei Times accessed August 25, 2008.
  5. ^ "In Memoriam: UC San Diego Pathology Professor Harvey Itano, MD, PhD, 1920-2010". Archived from the original on 2011-06-29. Retrieved 2010-06-08.
  6. ^ Doolittle, Russell F. (2014). "Biographical Memoirs: Harvey Itano 1920-2010" (PDF).
  7. ISBN 978-0688079963
    .
  8. The Los Angeles Times
    .
  9. ^ a b Ted Goertzel and Ben Goertzel. Linus Pauling: A Life in Science and Politics. New York:BasicBooks, 1995. p. 90
  10. ^ a b "The Register of Harvey Itano Papers 1946 - 2000 Archived 2012-06-14 at the Wayback Machine", MSS 0226, Mandeville Special Collections Library, Geisel Library, University of California, San Diego. Accessed August 25, 2008.
  11. PMID 20288558. Archived from the original
     on 2012-07-11. Retrieved 2008-08-25.
  12. S2CID 4167855
    .
  13. PMID 13560404
    .
Retrieved from "https://en.wikipedia.org/w/index.php?title=Harvey_Itano&oldid=1259474676"