William Jencks

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William Platt Jencks
National Academy of Sciences
Brandeis University
Signature

William Platt Jencks (August 15, 1927 – January 3, 2007) was an American

enzymes, using concepts drawn from organic chemistry to understand their mechanisms.[1][2][3]

Career

Jencks graduated from

R. B. Woodward of the Harvard University Department of Chemistry. In 1957, he moved to the new graduate program in biochemistry at Brandeis University
. He became professor emeritus in 1996.

Much of his career focused on reaction mechanisms used by

Circe Effect, to increase the reactivity of their bound substrates.[5][6] In this work he proposed the frequently misunderstood concept of one-way enzymes — enzymes that are more effective catalysts in one direction than in the other.[7] Many of these research interests were explored in his influential[4]: 183  text Catalysis in Chemistry and Enzymology.[8] Jencks published close to 400 scientific papers during his career.[9]

Jencks was a co-founder of the biannual Winter Enzyme Mechanisms Conference. He was memorialized at the 20th Enzyme Mechanisms Meeting in St. Pete Beach, Florida, several days after his death.

Honors and awards

Jencks was a recipient of the 1962

National Academy of Sciences in 1971.[9] Jencks was also a foreign member of the Royal Society[4] and a member of the American Philosophical Society.[10]

Personal life

Jencks's father, Gardner Jencks, was a pianist and composer.

Penelope Jencks-Hurwitz
, and John Cheetham.

Selected bibliography

References

  1. ^ John Lowenstein (February 1, 2007). "In Memoriam William Jencks". Archived from the original on 2019-12-21.
  2. ^ Stu Borman (2007). "Enzymologist William Jencks Dies at 79". Retrieved 2008-08-04.
  3. ^
    PMID 9242900
    .
  4. ^ .
  5. ^ Jencks, W. P. (1975). "Binding energy, specificity and enzyme catalysis: the Circe effect". Adv. Enzymol. Relat. Areas Biochem. 43: 219–410.
  6. PMID 16593049
    .
  7. ^ It is important to understand that this does not imply any violation of thermodynamic principles, because reactions always proceed toward equilibrium, regardless where the process starts.
  8. .
  9. ^ .
  10. ^ Richard, John P.; Jack F. Kirsch (2009). "William Platt Jencks". Proceedings of the American Philosophical Society. 153 (1): 97.

External links