Clear cell acanthoma

Clear cell acanthoma
Clear cell acanthoma (Degos)
Specialty	Oncology

Clear cell acanthoma (also known as Acanthome cellules claires of Degos and Civatte, Degos acanthoma, and Pale cell acanthoma) is a benign clinical and histological

Clear cell acanthoma is characterized by a sharply demarcated psoriasiform epidermal hyperplasia composed of a proliferation of slightly enlarged keratinocytes, and basal cells with pale-staining glycogen-rich cytoplasm, mild spongiosis and scattered neutrophils, which may form small intraepidermal microabscesses. Oedematous dermal papillae are typically seen with increased vascularity and a mixed inflammatory infiltrate including lymphocytes, plasma cells and neutrophils.

Treatment

Simple surgical excision is curative. ^{[1]: 636 [2]: 777}

See also

• Epidermis
• List of cutaneous conditions
• List of cutaneous neoplasms associated with systemic syndromes

References