Compound analgesic
Compound analgesics are those with multiple active ingredients; they include many of the stronger prescription analgesics.
Active ingredients that have been commonly used in compound analgesics include:
- aspirin or ibuprofen
- caffeine
- codeine or oxycodone
- paracetamol (acetaminophen)
- phenacetin
There is evidence that a compound of two analgesics with different mechanism of action can have an increased painkilling effect over the sum of the effect of each individual analgesic.[1]
Several such formulations have disappeared from
Lenoltec is a compound analgesic that comes in four strengths:
| No. | Acetaminophen mg |
Caffine mg |
Codene mg |
DIN |
|---|---|---|---|---|
| 1 | 300 | 15 | 8 | 00653233 [1] |
| 2 | 300 | 15 | 15 | 00653241 [2] |
| 3 | 300 | 15 | 30 | 00653276 [3] |
| 4 | 300 | 0 | 60 | 00621463 [4] |
Another example is Bex, a once popular Australian compound analgesic which is no longer sold. It contained 42% aspirin, 42% phenacetin, plus caffeine.[2]
The United States Food and Drug Administration also now requires that manufacturers of compound analgesics unequivocally state each ingredient's purpose.[citation needed]
References
- PMID 6486130.
- ^ Powerhouse Museum. "Packet of Bex Powders". Powerhouse Museum, Australia. Retrieved 10 July 2011.
External links
- APC definition and brief history.
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