Dopaminergic
Look up dopaminergic in Wiktionary, the free dictionary.
Dopaminergic means "related to
VMAT2
.
Supplements and drugs
The following are examples of dopaminergic substances:
Precursors
- Dopamine L-tyrosine are used as dietary supplements. L-DOPA (Levodopa), another precursor, is used in the treatment of Parkinson's disease.
Receptor agonists
- depression and anxiety.
Receptor antagonists/receptor blockers
- thiothixene, and trifluoperazine, the atypical antipsychotics such as amisulpride, clozapine, olanzapine, quetiapine (Seroquel), risperidone (Risperdal), sulpiride, and ziprasidone, and antiemetics like domperidone, metoclopramide, and prochlorperazine, among others, which are used in the treatment of schizophrenia and bipolar disorder as antipsychotics, and nausea and vomiting.
Reuptake inhibitors/transporter blockers
- street drugs.
- antihypertensives, and in the past as antipsychotics.
Releasing agents
- street drugs.
"Activity enhancers"
- Dopamine "activity enhancers" such as medical disorders. To date, only phenylethylamine and tryptamine have been identified as endogenous "activity enhancers".[2]
Monoamine oxidase inhibitors
- dimethyltryptamine (DMT) via inhibiting their metabolism.
Dopamine synthesis enhancers
- Tyrosine hydroxylase (TH) mRNA upregulators such as bromantane and low dose aspirin.[3][4] Bromantane's upregulation of TH may persist for a time (up to at least one month) after its discontinuation based on data related to its efficacy in treating asthenic disorders in Russia.[5]
Other enzyme inhibitors
- .
- positive punishment from its unpleasant effects deters drug consumption.[6]
- 3,4-dihydroxystyrene), which is currently only a research chemical with no suitable therapeutic indications, likely because such drugs would induce the potentially highly dangerous hyperphenylalaninemia or phenylketonuria.
- antihypertensiveagent.
- antihypertensiveagents.
- Others such as S-adenosyl-L-methionine(SAMe)
See also
- Adrenergic
- Cholinergic
- Cocaine and amphetamine regulated transcript (CART)
- GABAergic
- Histaminergic
- Serotonergic