Homocysteine desulfhydrase
| homocysteine desulfhydrase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme homocysteine desulfhydrase (EC 4.4.1.2) catalyzes the chemical reaction
- L-homocysteine + H2O = hydrogen sulfide + NH3 + 2-oxobutanoate (overall reaction)
- (1a) L-homocysteine = hydrogen sulfide + 2-aminobut-2-enoate
- (1b) 2-aminobut-2-enoate = 2-iminobutanoate (spontaneous)
- (1c) 2-iminobutanoate + H2O = 2-oxobutanoate + NH3 (spontaneous)
This enzyme belongs to the family of
.References
- Kallio RE (September 1951). "Function of pyridoxal phosphate in desulfhydrase systems of Proteus morganii". The Journal of Biological Chemistry. 192 (1): 371–7. PMID 14917685.
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