Mucin 7

MUC7
Identifiers
Gene ontology
Molecular function	protein binding;
Cellular component	Golgi lumen; extracellular region; extracellular exosome; plasma membrane;
Biological process	O-glycan processing; stimulatory C-type lectin receptor signaling pathway; antimicrobial humoral immune response mediated by antimicrobial peptide;
	Sources:Amigo / QuickGO

Ensembl


ENSG00000171195


n/a

UniProt


Q8TAX7


n/a

RefSeq (mRNA)


NM_152291 NM_001145006 NM_001145007


n/a

RefSeq (protein)


NP_001138478 NP_001138479 NP_689504


n/a

Location (UCSC)

Chr 4: 70.43 – 70.48 Mb

n/a

PubMed search

^[2]

n/a

Wikidata

View/Edit Human

Mucin-7 is a

placental mammals, but not marsupials.^[5]

Human variations

macaques, 10-11 for baboons and 11-12 for green monkeys.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171195 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
PMID 8838308
.

^ "Entrez Gene: MUC7 mucin 7, secreted".

^
PMID 27558399. This article contains quotations from this source, which is available under the Creative Commons Attribution 4.0 International (CC BY 4.0)
license.

Further reading

Zalewska A, Zwierz K, Zółkowski K, Gindzieński A (2002). "Structure and biosynthesis of human salivary mucins". Acta Biochimica Polonica. 47 (4): 1067–79.
PMID 11996097
.

Bobek LA, Tsai H, Biesbrock AR, Levine MJ (September 1993). "Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7)". The Journal of Biological Chemistry. 268 (27): 20563–9.
PMID 7690757
.

Troxler RF, Iontcheva I, Oppenheim FG, Nunes DP, Offner GD (October 1997). "Molecular characterization of a major high molecular weight mucin from human sublingual gland". Glycobiology. 7 (7): 965–73.
PMID 9363439
.

Prakobphol A, Thomsson KA, Hansson GC, Rosen SD, Singer MS, Phillips NJ, Medzihradszky KF, Burlingame AL, Leffler H, Fisher SJ (April 1998). "Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand activity". Biochemistry. 37 (14): 4916–27.
PMID 9538010
.

Kirkbride HJ, Bolscher JG, Nazmi K, Vinall LE, Nash MW, Moss FM, Mitchell DM, Swallow DM (May 2001). "Genetic polymorphism of MUC7: allele frequencies and association with asthma". European Journal of Human Genetics. 9 (5): 347–54.
PMID 11378823
.

Guo JM, Zhang Y, Cheng L, Iwasaki H, Wang H, Kubota T, Tachibana K, Narimatsu H (July 2002). "Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12". FEBS Letters. 524 (1–3): 211–8.
S2CID 84453381
.

Cheng L, Tachibana K, Zhang Y, Guo J, Kahori Tachibana K, Kameyama A, Wang H, Hiruma T, Iwasaki H, Togayachi A, Kudo T, Narimatsu H (November 2002). "Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T10". FEBS Letters. 531 (2): 115–21.
S2CID 221288147
.

Banderas-Tarabay JA, Zacarías-D'Oleire IG, Garduño-Estrada R, Aceves-Luna E, González-Begné M (2003). "Electrophoretic analysis of whole saliva and prevalence of dental caries. A study in Mexican dental students". Archives of Medical Research. 33 (5): 499–505.
PMID 12459324
.

Wang H, Tachibana K, Zhang Y, Iwasaki H, Kameyama A, Cheng L, Guo J, Hiruma T, Togayachi A, Kudo T, Kikuchi N, Narimatsu H (January 2003). "Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14". Biochemical and Biophysical Research Communications. 300 (3): 738–44.
PMID 12507512
.

Soares RV, Siqueira CC, Bruno LS, Oppenheim FG, Offner GD, Troxler RF (June 2003). "MG2 and lactoferrin form a heterotypic complex in salivary secretions". Journal of Dental Research. 82 (6): 471–5.
S2CID 23276142
.

Ge J, Catt DM, Gregory RL (November 2004). "Streptococcus mutans surface alpha-enolase binds salivary mucin MG2 and human plasminogen". Infection and Immunity. 72 (11): 6748–52.
PMID 15501816
.

Grys TE, Siegel MB, Lathem WW, Welch RA (March 2005). "The StcE protease contributes to intimate adherence of enterohemorrhagic Escherichia coli O157:H7 to host cells". Infection and Immunity. 73 (3): 1295–303.
PMID 15731026
.

Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8.
S2CID 4427026
.

Bruno LS, Li X, Wang L, Soares RV, Siqueira CC, Oppenheim FG, Troxler RF, Offner GD (October 2005). "Two-hybrid analysis of human salivary mucin MUC7 interactions". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1746 (1): 65–72.
PMID 16203048
.

Li S, Intini G, Bobek LA (July 2006). "Modulation of MUC7 mucin expression by exogenous factors in airway cells in vitro and in vivo". American Journal of Respiratory Cell and Molecular Biology. 35 (1): 95–102.
PMID 16514118
.

v
t
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Protein, glycoconjugate: glycoproteins and glycopeptides
Mucoproteins
Mucin

CD43

CD164

MUC1

MUC2

MUC3A

MUC3B

MUC4

MUC5AC

MUC5B

MUC6

MUC7

MUC8

MUC12

MUC13

MUC15

MUC16

MUC17

MUC19

MUC20

Other

Haptoglobin

Intrinsic factor

Orosomucoid

Peptidoglycan

Phytohaemagglutinin

Ovomucin

Proteoglycans
CS/DS

Decorin

Biglycan

Versican

HS/CS

Testican

Perlecan

CS

Chondroitin sulfate proteoglycans: Aggrecan

Neurocan

Brevican

CD44

CSPG4

CSPG5

Platelet factor 4

Structural maintenance of chromosomes 3

KS

Fibromodulin

Lumican

Keratocan

HS

Syndecan 1

Other

Activin and inhibin

ADAM

Alpha 1-antichymotrypsin

Apolipoprotein H

CD70

Asialoglycoprotein

Avidin

B-cell activating factor

4-1BB ligand

Cholesterylester transfer protein

Clusterin

Colony-stimulating factor

Hemopexin

Lactoferrin

Membrane glycoproteins

Myelin protein zero

Osteonectin

Protein C

Protein S

Serum amyloid P component

Sialoglycoprotein
CD43

Glycophorin

Glycophorin C

Thrombopoietin

Thyroglobulin

Thyroxine-binding proteins

Transcortin

Tumor necrosis factor alpha

Uteroglobin

Vitronectin

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Retrieved from "https://en.wikipedia.org/w/index.php?title=Mucin_7&oldid=1171077799"

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000171195 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8838308-3] PMID 8838308
.

[entrez-4] "Entrez Gene: MUC7 mucin 7, secreted".

[Xu_Pavlidis_Thamadilok_Redwood_2016-5] 
PMID 27558399. This article contains quotations from this source, which is available under the Creative Commons Attribution 4.0 International (CC BY 4.0)
license.

[2]

[5]