Olfactory mucosa

Source: Wikipedia, the free encyclopedia.
Olfactory mucosa
Details
SystemOlfactory system
Identifiers
Latinpars olfactoria tunicae mucosae nasi,
regio olfactoria tunicae mucosae nasi
MeSHD009831
Anatomical terminology

The olfactory mucosa is the

olfactory pathway, as well as supporting cells. The neurons' dendrites project towards the nasal cavity while their axons ascend through the cribriform plate[1] as the olfactory nerves.[3]

The part of the nasal cavity that is lined with olfactory mucosa is known as the olfactory region (pars olfactoria tunicae mucosae nasi),

respiratory mucosa is known as the respiratory region.[4]

Structure

Olfactory mucosa lines about 5cm2 of the posterosuperior parts of the lateral nasal wall. Parts of the nasal cavity lined by olfactory mucosa include: parts of the roof of the nasal cavity, the superior nasal concha and some upper parts of the middle nasal concha, parts of the nasal septum, and the sphenoethmoidal recess.[5]

The olfactory mucosa is thicker and lighter in colour (yellowish-brown) in comparison to the (pinkish) respiratory mucosa lining the rest of the nasal cavity.[1]

Glands of the olfactory mucosa secrete a mostly serous fluid.[5]

Histology

The olfactory mucosa consists of the

neurons.[6]

In

basal cells, the stem cells that continuously give rise to new olfactory receptor neurons and sustentacular cells.[7]

odorant binding protein.[9][10]

Physiology

The mucus protects the olfactory epithelium and allows odors to dissolve so that they can be detected by olfactory receptor neurons.[8][verification needed]

Research

Adult stem cell harvesting

Cells in the olfactory mucosa have been used in clinical trials for adult stem cell therapeutic treatments and successfully harvested for future applications.[11]

CB1 receptors and obesity

Type 1 cannabinoid receptors (CB1 receptors) are present in the sustentacular cells of the olfactory mucosa, in the periglomerular cells of the olfactory bulb, and in the anterior olfactory nucleus and olfactory cortices. A study in 2008 in mice has shown that the level of CB1 expression in various brain regions, including the olfactory nucleus, is modulated by diet-induced obesity.[12]

See also

References

  1. ^
    ISBN 978-0-7295-3752-0
    .
  2. ^ a b "pars olfactoria tunicae mucosae nasi". TheFreeDictionary.com. Retrieved 2023-06-12.
  3. ^ "fila olfactoria". TheFreeDictionary.com. Retrieved 2023-06-12.
  4. ^ "pars respiratoria tunicae mucosae". TheFreeDictionary.com. Retrieved 2023-06-12.
  5. ^
    OCLC 1201341621.{{cite book}}: CS1 maint: location missing publisher (link
    )
  6. S2CID 25263022{{citation}}: CS1 maint: numeric names: authors list (link
    )
  7. PMID 11891623
  8. ^
    PMID 6052394
  9. ISBN 978-1-4160-2945-8
    .
  10. PMID 11058764
  11. ^ Eskitis Institute for Cell and Molecular Therapies
  12. PMID 22832483
    .
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