Propiophenone
Names | |
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Preferred IUPAC name
1-Phenylpropan-1-one | |
Other names
Ethyl phenyl ketone, BzEt
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Identifiers | |
3D model (
JSmol ) |
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard
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100.002.053 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C9H10O | |
Molar mass | 134.178 g·mol−1 |
Appearance | Colorless liquid |
Density | 1.0087 g/mL |
Melting point | 18.6 °C (65.5 °F; 291.8 K) |
Boiling point | 218 °C (424 °F; 491 K) |
Insoluble | |
-83.73·10−6 cm3/mol | |
Related compounds | |
Related ketones
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Acetophenone Butyrophenone |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Propiophenone (
organic solvents
. It is used in the preparation of other compounds.
Production
Propiophenone can be prepared by
alumina at 450–550 °C:[1]
- C6H5CO2H + CH3CH2CO2H → C6H5C(O)CH2CH3 + CO2 + H2O
Uses
It is an intermediate in the synthesis of the pharmaceuticals phenmetrazine and propoxyphen.[1][4][5]
Other drugs made from propiophenone include the following: PDM-35, Eprazinone, Methcathinone (leading to ephedrine), Trimebutine, Amfepramone, Diphepanol, Metamfepramone, Etoxadrol, Hydroxyphenamate, Phendimetrazine, Iminophenimide, Bencisteine, Flumecinol, Pyrroliphene, Perisone,
References
- ^ ISBN 978-3527306732.
- .
- .
- ^ "propiophenone". Merriam-Webster.com. Merriam-Webster. Retrieved 2 June 2012.
- .