Ro01-6128

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Ro01-6128
Identifiers
  • ethyl diphenylacetylcarbamate
JSmol)
  • c2ccccc2C(C(=O)NC(=O)OCC)c1ccccc1
  • InChI=1S/C17H17NO3/c1-2-21-17(20)18-16(19)15(13-9-5-3-6-10-13)14-11-7-4-8-12-14/h3-12,15H,2H2,1H3,(H,18,19,20)
  • Key:ILSZPWZFQHSKLW-UHFFFAOYSA-N
  (verify)

Ro01-6128 is a drug used in scientific research, which acts as a selective

positive allosteric modulator for the metabotropic glutamate receptor subtype mGluR1.[1][2][3] It was derived by modification of a lead compound found via high-throughput screening, and was further developed to give the improved compound Ro67-4853.[4]

References

  1. PMID 11606768
    .
  2. S2CID 2719603
    .
  3. PMID 18625258
    .
  4. PMID 12564473
    .
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