Vascular disease

Source: Wikipedia, the free encyclopedia.
Vascular disease
Veins and arteries
SpecialtyAngiology Edit this on Wikidata
TypesPeripheral artery disease,[1] Renal artery stenosis[2]
Diagnostic methodVenography, Ultrasound[3]
TreatmentQuit smoking, Lower cholesterol[4]

Vascular disease is a class of diseases of the vessels of the

Coronary heart disease for example, is the leading cause of death for men and women in the United States.[5]

Types

There are several types of vascular disease, including venous diseases, and arterial diseases, and signs and symptoms vary depending on the disease. Those of the arterial system are associated with blood supply to tissues and its obstruction due to blockages or narrowing. In the

venous system disorders are often caused by a slow return of blood due to insufficient valves, or to a blood clot.[6]

Venous disease

Most disorders of the veins involve obstruction such as a

valves, or both of these.[7][8][9] Other conditions may be due to inflammation
.

Phlebitis

Phlebitis is the inflammation of a vein. It is usually accompanied by a blood clot when it is known as thrombophlebitis. When the affected vein is a superficial vein in the leg, it is known as superficial thrombophlebitis, and unlike deep vein thrombosis there is little risk of the clot breaking off as an embolus.[10]

Venous insufficiency

Venous insufficiency is the most common disorder of the venous system, and is usually manifested as either

endovenous thermal ablation (using radiofrequency or laser energy), vein stripping, ambulatory phlebectomy, foam sclerotherapy, laser, or compression.[citation needed
]

Postphlebitic syndrome is venous insufficiency that develops following deep vein thrombosis.[11]

Venous thrombosis

anticoagulation to prevents clots or to reduce the size of the clot. Intermittent pneumatic compression is a method used to improve venous circulation in cases of edema or in those at risk from a deep vein thrombosis.[citation needed
]

A clot can also form in a

superficial venous thrombosis) which is normally not clinically significant, but the thrombus can migrate into the deep venous system where it can also give rise to a pulmonary embolism.[12]

Portal hypertension

The

hepatic vein (Budd Chiari syndrome) or compression from tumors or tuberculosis lesions. When the pressure increases in the portal vein, a collateral circulation develops, causing visible veins such as esophageal varices.[citation needed
]

Vascular anomalies

A vascular anomaly can be either a vascular tumor or a birthmark, or a vascular malformation.

vascular malformations.[16] A severe venous malformation can involve the lymph vessels as a lymphaticovenous malformation.[14]

Arterial disease

Erythromelalgia in a 77-year-old woman

Lymphatic disease

Mechanism

Endothelium lines the inner wall of the vessel

Vascular disease is a pathological state of large and medium muscular arteries and is triggered by

endothelial cell dysfunction.[22]

Because of factors like

endothelial cells become active.[23]

The process causes thickening of the vessel wall, forming a plaque that consists of proliferating

The plaque results in restricted blood flow, decreasing the amount of oxygen and nutrients that reach certain organs.[26]

This plaque can also rupture, causing the formation of clots.[27]

Diagnosis

Diagnosing vascular disease can be complex due to the variety of symptoms vascular diseases can cause. Reviewing a patient's

blood flow in a patient's legs.[28][29]

Treatment

Peripheral vascular disease-ulcer

Treatment varies based on the type of vascular disease being treated. In treating renal artery disease, a 2014 study indicates that balloon angioplasty can improve diastolic blood pressure and potentially reduce antihypertensive drug requirements.[30] In the case of peripheral artery disease, treatment to prevent complications is important; without treatment, sores or gangrene (tissue death) may occur.[citation needed]

More generally, treatments for vascular disease may include:[4]

  • Lowering cholesterol levels
  • Lowering blood pressure
  • Lowering blood glucose
  • Changes in diet
  • Increasing physical activity (as recommended by a healthcare provider)
  • Weight loss
  • Quitting smoking
  • Stress reduction

References

  1. ^ a b "Peripheral Arterial Disease: MedlinePlus". www.nlm.nih.gov. Retrieved 2015-06-23.
  2. ^ a b "Renal Artery Stenosis". www.niddk.nih.gov. Retrieved 2015-06-23.
  3. ^ a b "Vascular Diseases: MedlinePlus". www.nlm.nih.gov. Retrieved 2015-06-23.
  4. ^ a b "How Is Peripheral Arterial Disease Treated? - NHLBI, NIH". www.nhlbi.nih.gov. Retrieved 2015-06-23.
  5. ^ "Coronary Artery Disease". medlineplus.gov. Retrieved 13 February 2023.
  6. . Retrieved 2016-02-02.
  7. .
  8. ^ Publishing, Licorn (9 April 2013). "The venous valves of the lower limbs". Servier - Phlebolymphology. Retrieved 9 January 2023.
  9. ^ "20.1 Structure and Function of Blood Vessels - Anatomy and Physiology 2e | OpenStax". openstax.org. Retrieved 25 January 2023.
  10. PMID 29478266
    .
  11. .
  12. .
  13. .
  14. ^ .
  15. .
  16. .
  17. ^ "Erythromelalgia". nhs.uk. 2017-10-18. Retrieved 2019-01-04.
  18. ^ "Thromboangiitis obliterans: MedlinePlus Medical Encyclopedia". www.nlm.nih.gov. Retrieved 2015-06-23.
  19. ^ "Raynaud's Disease: MedlinePlus". www.nlm.nih.gov. Retrieved 2015-06-23.
  20. ^ "Disseminated intravascular coagulation (DIC): MedlinePlus Medical Encyclopedia". www.nlm.nih.gov. Retrieved 2015-06-25.
  21. ^ "Stroke". nhs.uk. 2017-10-24. Retrieved 2022-06-29.
  22. PMID 24250251
    .
  23. .
  24. .
  25. .
  26. .
  27. .
  28. ^ "How Is Peripheral Arterial Disease Diagnosed? - NHLBI, NIH". www.nhlbi.nih.gov. Retrieved 2015-06-23.
  29. PMID 24711093
    .
  30. .

Further reading

External links