Acetrizoic acid

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Acetrizoic acid
Skeletal formula
Space-filling model
Clinical data
Trade namesUrokon, Triurol, Salpix, others
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 3-Acetamido-2,4,6-triiodobenzoic acid
JSmol)
  • O=C(Nc1c(I)c(c(I)cc1I)C(=O)O)C
  • InChI=1S/C9H6I3NO3/c1-3(14)13-8-5(11)2-4(10)6(7(8)12)9(15)16/h2H,1H3,(H,13,14)(H,15,16) checkY
  • Key:GNOGSFBXBWBTIG-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Acetrizoic acid is a pharmaceutical drug that was used as an

X-ray imaging.[1][2] It was applied in form of its salt, sodium acetrizoate, but is no longer in clinical use.[3]

Chemistry and mechanism of action

The substance has high

water-soluble. The three iodine atoms in the molecule readily absorb X-rays and are therefore responsible for its usability as a contrast medium.[3]

History

Acetrizoate was developed by V.H. Wallingford of

sodium diatrizoate, a closely related compound.[4]

Trade names

Trade names include Urokon, Triurol and Salpix, as well as Gastrografina and Urografina in Portugal.

References

  1. ^ International Drug Names: Acetrizoic acid.
  2. PMID 20641966. {{cite journal}}: Cite journal requires |journal= (help
    )
  3. ^ a b "Acetrizoate sodium". Online Medical Dictionary. University of Newcastle upon Tyne. March 5, 2000. Retrieved 2007-11-14.
  4. ^
    PMID 2115244
    .
  5. PMID 15422724
    .
  6. PMID 13323329
    .
  7. PMID 13039633
    .
  8. PMID 13103941
    .
  9. PMID 13258064
    .
  10. PMID 13485425
    .
  11. PMID 13661846
    .
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