Iopentol
Intravenous, by mouth, injection into body cavities | |
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| Pharmacokinetic data | |
| Protein binding | Low |
| Metabolism | None |
| Elimination half-life | 2 hrs (intravenous) |
| Excretion | 98% via kidneys |
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JSmol) | |
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Iopentol (trade name Imagopaque) is a pharmaceutical drug that was used as a
Medical uses
Uses included
It can be injected
Contraindications
Hysterosalpingography is contraindicated during acute inflammation in the
Adverse effects
Adverse effects include nausea, vomiting, headache, as well as low or high blood pressure or heart rate. Allergy-like reactions such as rashes are usually mild; glottal edema, shock and cardiac arrest are rare.[2]
Interactions
Iodine-131, a radioactive isotope used for thyroid imaging (scintigraphy) and therapy of thyroid cancers, can be less effective when used within two to six weeks after application of iopentol because of residual iodine in the body.[2]
Pharmacology
Chemistry and mechanism of action
Iopentol is an iodine-containing, water-soluble radiocontrast agent. The iodine atoms readily absorb
A phase III clinical trial concluded that iopentol produces images of a similarly high quality as iohexol, and that it is equally well tolerated by patients.[1]
Pharmacokinetics
After intravenous injection, iopentol is distributed in the