Iopanoic acid
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AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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Melting point | 162–163 °C (324–325 °F) |
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Iopanoic acid is an
thyrotoxicosis (thyroid storm) and significant morbidity (e.g., myocardial infarction
, or stroke) for rapid control of elevated plasma triiodothyronine concentrations. The use of iopanoic acid for treatment of thyrotoxicosis has been discontinued in the United States.
In addition to inhibiting deiodinase enzymes, iopanoic acid is also a substrate of type 1 deiodinase. Iopanoic acid underwent monodeiodination in the presence of type 1 deiodinase in a microsomal mouse liver preparation.[1]
References
- PMID 22434082.