Amos Bairoch

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"Bairoch" redirects here. For the economic historian, see Paul Bairoch.

Amos Bairoch
Amos Bairoch
Born (1957-11-22) 22 November 1957 (age 66)[1]
Alma materUniversity of Geneva[3]
Known for
Awards
Scientific career
Fields
InstitutionsSwiss Institute of Bioinformatics
Websiteweb.expasy.org/groups/people/amos.html

Amos Bairoch (born 22 November 1957)[1] is a Swiss bioinformatician[3][6][7] and Professor of Bioinformatics at the Department of Human Protein Sciences of the University of Geneva where he leads the CALIPHO group[8] at the Swiss Institute of Bioinformatics (SIB) combining bioinformatics, curation, and experimental efforts to functionally characterize human proteins.[9]

His father was the economic historian Paul Bairoch.

Education

His first project as a

PhD student was the development of PC/Gene,[10] an MS-DOS–based software package for the analysis of protein and nucleotide sequences. PC/Gene was commercialized, first by a Swiss company (Genofit) then by Intelligenetics in the US which was later bought by Oxford Molecular.[citation needed
]

Research

His main work[2] is in the field of protein sequence analysis and more particularly in the development of databases and software tools for this purpose. His most important contribution is the input of human knowledge by careful manual annotation in protein-related data.[11]

While working on PC/Gene he started to develop an annotated protein sequence database which became

Swiss-Prot and was first released in July 1986.[12] From 1988 onward it has been a collaborative project with the Data Library group of the European Molecular Biology Laboratory which later evolved into the European Bioinformatics Institute
(EBI).

The

TrEMBL, and the American Protein Information Resource (PIR)
databases.

In 1988, he started to develop PROSITE,[15] a database of protein families and domains. A little while later he created ENZYME,[16][17][18][19][20] a nomenclature database on enzymes as well as SeqAnalRef,[21] a sequence analysis bibliographic reference database.[22][23]

In collaboration with

ExPASy.[24]
What was intended as a prototype grew rapidly into a major site that provides access to the many databases produced partially or completely in Geneva as well as many tools for the analysis of proteins (proteomics).

In 1998, with colleagues in Geneva and Lausanne, he was one of the founders of the SIB Swiss Institute of Bioinformatics, whose mission is to establish in Switzerland a center of excellence in the field of bioinformatics with an emphasis on research, education, services and the developments of databases and tools.[25]

In November 1997, together with Ron Appel and Denis Hochstrasser, he founded GeneBio (Geneva Bioinformatics SA), a company involved in biological knowledge. In April 2000, the above persons with Keith Rose and Robin Offord founded GeneProt (Geneva Proteomics), a high throughput proteomics company that ceased operations in 2005.[26]

Since 2009, in the framework of the CALIPHO group, directed by himself and Lydie Lane, he is involved in the development of neXtProt[27][28][29] a resource which aims to provide life scientists with a broad spectrum of knowledge on all human proteins.

He is also involved in the development of the Cellosaurus a knowledge resource on cell lines.

According to

scientific journals have been published in Nucleic Acids Research,[30][31][32][33][34] the Biochemical Journal,[35][36] Nature,[37] Briefings in Bioinformatics,[38] and Database.[39]

Awards and honours

Bairoch was the recipient of the 1993 Friedrich Miescher Award from the Swiss Society of Biochemistry, the 1995 Helmut Horten Foundation Incentive Award, the 2004 Pehr Edman award, the 2004 European Latsis Prize, the 2010 Otto Naegeli prize, the 2011 HUPO Distinguished Achievement Award in Proteomic Sciences.,[40] the 2013 EUPA proteomics pioneer award,[1] and in 2018 the ABRF Award.

Quotes

As the process keeps going down we're reaching the point where every genome that can be sequenced will be sequenced.[41]

References

  1. ^
    doi:10.1016/j.euprot.2013.12.002
    .
  2. ^ a b c Amos Bairoch publications indexed by Google Scholar
  3. ^ a b "Amos Bairoch's home page". ExPASy. Archived from the original on 14 February 2014.
  4. PMID 2041811
    .
  5. PMID 12824418
    .
  6. ^ a b Amos Bairoch's publications indexed by the Scopus bibliographic database. (subscription required)
  7. ^ Amos Bairoch publications from Europe PubMed Central
  8. ^ "CALIPHO (Computer Analysis and Laboratory Investigation of Proteins of Human Origin) group page on the SIB website". Archived from the original on 20 April 2013.
  9. ^ "SIB's Bairoch to Step Down as Swiss-Prot Director to Launch New Human Protein Resource". GenomeWeb.com. Archived from the original on 20 February 2012.
  10. PMID 3273189
    .
  11. PMID 18849571
    .
  12. PMID 10812477
    . – a historical account by Bairoch.
  13. PMID 10803381
    .
  14. PMID 16381842
    .
  15. PMID 9847184
    .
  16. PMID 10592255
    .
  17. PMID 9847212
    .
  18. PMID 8594586
    .
  19. PMID 7937072
    .
  20. PMID 8332535
    .
  21. PMID 2059856
    .
  22. PMID 2041810
    .
  23. PMID 18003654
    .
  24. PMID 8073505
    .
  25. PMID 18617148
    .
  26. ^ "With No New Deals, GeneProt to Close Its Doors". GenomeWeb.com. June 2005. Archived from the original on 11 February 2011.
  27. PMID 22139911
    .
  28. PMID 25593349
    .
  29. PMID 23205526
    .
  30. PMID 15608167
    .
  31. PMID 12520024
    .
  32. PMID 11125043
    .
  33. PMID 12520011
    .
  34. PMID 15608177. Open access icon
  35. PMID 8687420
    .
  36. PMID 8352747
    .
  37. S2CID 4336941
    .
  38. PMID 12230035
    .
  39. PMID 21205783
    .
  40. ^ "HUPO Distinguished Awards". HUPO. Archived from the original on 5 June 2013.
  41. PMID 18769412
    .
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