Benzylthiouracil

Benzylthiouracil

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	H03BA03 (WHO)
Pharmacokinetic data
Excretion	Renal
Identifiers
IUPAC name 1-(1-cyclohexa-2,4-dienylmethyl)-7-thia- 3,5-diazabicyclo[4.1.0]hepta-3,5-dien-2-one
JSmol)	Interactive image
SMILES S=C1N/C(=C\C(=O)N1)Cc2ccccc2
InChI InChI=1S/C11H10N2OS/c14-10-7-9(12-11(15)13-10)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H2,12,13,14,15) Y Key:PNXBXCRWXNESOV-UHFFFAOYSA-N Y
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Benzylthiouracil (BTU) is an antithyroid preparation. It is a thioamide, closely related to propylthiouracil.

Adverse effects

Benzylthiouracil has been associated with severe adverse effects, notably vasculitis and subsequent ANCA-positive glomerulonephritis, as well as isolated reports of lung damage.^[1][2][3][4]

References