Diiodotyrosine

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Diiodotyrosine
Skeletal formula of diiodotyrosine
Ball-and-stick model of the diiodotyrosine molecule as a zwitterion
Names
Preferred IUPAC name
(2S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
Identifiers
3D model (
JSmol
)
ChemSpider
ECHA InfoCard
100.005.539 Edit this at Wikidata
IUPHAR/BPS
MeSH Diiodotyrosine
UNII
  • InChI=1S/C9H9I2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m0/s1 ☒N
    Key: NYPYHUZRZVSYKL-ZETCQYMHSA-N ☒N
  • InChI=1/C9H9I2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m0/s1
    Key: NYPYHUZRZVSYKL-ZETCQYMHBZ
  • Ic1cc(cc(I)c1O)C[C@@H](C(=O)O)N
Properties
C9H9I2NO3
Molar mass 432.982 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Diiodotyrosine (DIT) is a precursor in the production of

monoiodotyrosine at the other meta- position on the phenol
ring.

Function

DIT is a modulator of the enzyme thyroid peroxidase (which is involved in the production of thyroid hormones).[1]

thyroid follicle
).

Two molecules of DIT combine to make the thyroid hormone

thyroxine
('T4' and 'T3').

See also

References

External links