Bgee
| Miscellaneous | |
|---|---|
| License | CC0 1.0 Universal |
| Version | 15.1 |
| Curation policy | Manual curation of every study. |
Bgee is a
Bgee is based exclusively on curated, healthy wild-type, expression data (i.e., no gene knock-out, no treatment, no disease), to provide a comparable reference of healthy wild-type gene expression.
Bgee produces calls of presence/absence of expression, and of differential over-/under-expression, integrated along with information of gene orthology, and of homology between organs. This allows comparisons of expression patterns between species.
Bgee allows searches by gene, organ / tissue / cell type and developmental stage.
Bgee is a part of Global Core Biodata Resources (GCBRs) representing "critical components for ensuring the reproducibility and integrity of life sciences research." Bgee is also an ELIXIR Recommended Interoperability Resources that facilitate the FAIR-supporting activities in scientific research.
References
- ISBN 978-3-540-69827-2.
- PMID 33037820.
Further reading
- Niknejad A, Mungall CJ, Osumi-Sutherland D, Robinson-Rechavi M, Bastian F (2022). "Creation and unification of development and life stage ontologies for animals". arXiv:2206.12231 [q-bio.QM].
- Komljenovic A, Roux J, Wollbrett J, Robinson-Rechavi M, Bastian F (2018). "BgeeDB, an R package for retrieval of curated expression datasets and for gene list expression localization enrichment tests". F1000Research. 5: 2748. PMID 30467516.
- Haendel MA, Balhoff JP, Bastian FB, Blackburn DC, Blake JA, Bradford Y, et al. (2014). "Unification of multi-species vertebrate anatomy ontologies for comparative biology in Uberon". J Biomed Semantics. 5: 21. PMID 25009735.
External links
- "Bgee is a new ELIXIR Recommended Interoperability Resources". ELIXIR. 14 December 2023.
- "Bgee joins the Global Core Biodata Resources". GCB Global Biodata Coalition. 11 December 2023.
- "About Bgee". SIB Swiss Institute of Bioinformatics. 4 January 2021.